LEADER 04638nam 2200709 450 001 9910149745003321 005 20230525192748.0 010 $a1-61504-731-X 024 7 $a10.4199/C00143ED1V01Y201610NGL009 035 $a(CKB)3710000000935166 035 $a(MiAaPQ)EBC4731703 035 $a(OCoLC)962190531 035 $a(CaBNVSL)swl00406914 035 $a(MOCL)201610NGL009 035 $a(EXLCZ)993710000000935166 100 $a20161107d2017 fy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aNG2-glia (polydendrocytes) /$fArthur M. Butt 210 1$a[San Rafael, California] :$cMorgan & Claypool,$d2017. 215 $a1 online resource (54 pages) $ccolor illustrations 225 1 $aColloquium series on neuroglia in biology and medicine,$x2375-9917 ;$v# 9 300 $aPart of: Colloquium digital library of life sciences. 311 $a1-61504-730-1 320 $aIncludes bibliographical references (pages 25-38). 327 $a1. Introduction -- 327 $a2. Identification and lineage of NG2-glia (polydendrocytes) -- 2.1 Morphology and distribution of NG2-glia -- 2.2 Structure and function of NG2 (Cspg4) -- 2.3 Proliferation of NG2-glia and generation of oligodendrocytes -- 2.4 Multipotential nature of NG2-glia -- 327 $a3. Physiological characteristics of NG2-glia (polydendrocytes) -- 3.1 Ion channels -- 3.1.1 Potassium channels -- 3.1.2 Sodium channels -- 3.1.3 Calcium channels -- 3.1.4 Chloride channels -- 3.1.5 HCN channels -- 3.2 Neurotransmitter receptors -- 3.2.1 Glutamate receptors -- 3.2.2 GABA receptors -- 3.2.3 Purine receptors -- 3.2.4 Other neurotransmitter receptors -- 327 $a4. Synaptic signalling in NG2-glia (polydendrocytes) -- 4.1 Prominence of AMPA and GABAA receptor mediated signalling in NG2-glia -- 4.2 Functions of synaptic signalling in NG2-glia -- 4.3 Neurotransmitters and NG2-glial cell pathology -- 327 $a5. Pathological responses of NG2-glia (polydendrocytes) -- 5.1 Demyelination -- 5.2 Traumatic injury -- 5.3 Ageing -- 327 $a6. Concluding remarks -- References -- Author biography -- Titles of related interest. 330 3 $aClassically, the central nervous system (CNS) was considered to contain neurons and three main types of glial cells--astrocytes, oligodendrocytes, and microglia. Now, it has been clearly established that NG2-glia are a fourth glial cell type that are identified and defined by their expression of the NG2 chondroitin sulfate proteoglycan (Cspg4). NG2-glia differentiate into oligodendrocytes, the myelin-forming cells of the CNS, under the control of multiple extacellular and intrinsic factors. Due to this, NG2-glia are often referred to in the literature as oligodendrocyte progenitor cells (OPCs). The name polydendrocytes has been suggested for NG2-glia (OPCs), to emphasize their nature as a fourth distinct glial cell type. NG2-glia respond rapidly to neurotransmission via their synaptic connections with neurons and their repertoire of neurotransmitter receptors and ion channels. Bidirectional interactions between NG2-glia and neurons are also important for synaptic function and neuronal integrity. NG2-glia respond to most neuropathologies by increased proliferation and differentiation into oligodendrocytes, which is critical for replacing damaged myelin after injury and in demyelinating diseases, such as multiple sclerosis. There is also evidence NG2-glia are capable of generating astrocytes and neurons under some circumstances. The full capacity of NG2-glia is not yet clear, but their key function is the lifelong generation of oligodendrocytes, which is absolutely critical for CNS function and integrity. 410 0$aColloquium digital library of life sciences. 410 0$aColloquium series on neuroglia in biology and medicine ;$v# 9.$x2375-9917 606 $aNeuroglia 606 $aAstrocytes 606 $aNeuroglia 606 $aAstrocytes 610 $aNG2-Glia 610 $aoligodendrocyte precursor cell 610 $apolydendrocyte 610 $asynapse 610 $aglutamate 610 $apotassium 610 $aneuron-glial signalling 610 $aremyelination 615 0$aNeuroglia. 615 0$aAstrocytes. 615 2$aNeuroglia. 615 2$aAstrocytes. 676 $a611.0188 700 $aButt$b Arthur$01344575 801 0$bCaBNVSL 801 1$bCaBNVSL 801 2$bCaBNVSL 906 $aBOOK 912 $a9910149745003321 996 $aNG2-glia (polydendrocytes)$93364490 997 $aUNINA LEADER 01132nam0 22002891i 450 001 UON00291112 005 20231205103921.855 100 $a20070328d1972 |0itac50 ba 101 $aspa 102 $aES 105 $a|||| 1|||| 200 1 $aEstudios sobre el siglo 19. español$fpor Manuel Tuñon de Lara 205 $a2a edición 210 $a[Madrid]$cSiglo Veintiuno de España$d[1972] 215 $a284 p.$d18 cm. 410 1$1001UON00243921$12001 $aHistoria$1210 $aMadrid$cSiglo Veintiuno de Espana 606 $aSPAGNA$xStoria$xSec. 19.$3UONC061259$2FI 620 $aES$dMadrid$3UONL000218 676 $a946$cStoria della Spagna$v21 700 1$aTUÑON DE LARA$bManuel$3UONV048622$0402180 712 $aSiglo XXI de España$3UONV253860$4650 801 $aIT$bSOL$c20240220$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00291112 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI SPA III 1212 $eSI SP 5996 5 1212 996 $aEstudios sobre el siglo 19. espanol$91047079 997 $aUNIOR LEADER 04101nam 2201117z- 450 001 9910557472903321 005 20220111 035 $a(CKB)5400000000043069 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76445 035 $a(oapen)doab76445 035 $a(EXLCZ)995400000000043069 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aInteraction between Waves and Maritime Structures 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (284 p.) 311 08$a3-0365-0624-1 311 08$a3-0365-0625-X 330 $aThis book is the result of a stimulating Special Issue of Water, focusing on the "Interaction between waves and Maritime Structures". This broadly inclusive title allowed the gathering of articles on different topics of engineering concern, making the book appeal to both scientists and practical engineers. Original contributions on evergreen problems, such as wave overtopping at conventional and unconventional coastal structures, wave-induced pressures at vertical walls, hydraulic stability of rubble mound breakwaters and dynamics of crown-walls indeed represent the main core of the book; however, other intriguing research topics are also tackled, including the solution of the Navier-Stokes equations for biphase flows, the downscaling of large maritime structures in a physical lab, floating bodies mechanics and the numerical modeling of coastline evolution. 606 $aTechnology: general issues$2bicssc 610 $a2D experimental study 610 $aacceleration 610 $aastronomical tide 610 $abearing capacity 610 $abreakwater 610 $acoastal defenses 610 $acrown wall failure 610 $adamage 610 $adike 610 $adynamic response 610 $aelectrical platform 610 $aequivalent wave 610 $aexperimental investigation 610 $aexperiments 610 $afloating body 610 $afloating cylinder 610 $aflooding 610 $aflow depth 610 $aflow velocity 610 $afluid-structure interaction 610 $afluid-structure interactions 610 $afree surface 610 $agreen water 610 $ahydrodynamic response 610 $ahydroelastic similarity 610 $aimage analysis 610 $ain-situ observations 610 $alaboratory experiment 610 $alittoral drift 610 $ameteorological and ocean conditions 610 $amotion capturing 610 $an/a 610 $anotional permeability factor 610 $anumerical modelling 610 $aone-line equation 610 $aoverturning 610 $aport operation 610 $apulsating and impulsive conditions 610 $arecurve geometry 610 $arecurves 610 $arock armor stability 610 $aship motions 610 $ashoreline evolution 610 $asliding 610 $asloshing 610 $astorm surge 610 $astrain 610 $astructure response 610 $atransfer functions 610 $atwo-phase flows 610 $avalidation experiment 610 $aVenetian lagoon 610 $avertical seawalls 610 $avessel dimensions 610 $awater elevation database 610 $awater filled 610 $awave breaking 610 $awave decomposition 610 $awave gauges 610 $awave loads and pressures 610 $awave overtopping 610 $awave tank 610 $awet dam-break bore 615 7$aTechnology: general issues 700 $aBuccino$b Mariano$4edt$01324200 702 $aMartinelli$b Luca$4edt 702 $aBuccino$b Mariano$4oth 702 $aMartinelli$b Luca$4oth 906 $aBOOK 912 $a9910557472903321 996 $aInteraction between Waves and Maritime Structures$93036032 997 $aUNINA