LEADER 03882nam 22007452 450 001 9910454633503321 005 20151005020622.0 010 $a1-139-93145-8 010 $a1-107-20072-5 010 $a9786612001826 010 $a1-282-00182-5 010 $a0-511-48018-0 010 $a0-511-48098-9 010 $a0-511-47785-6 010 $a0-511-47633-7 010 $a0-511-75951-7 010 $a0-511-47937-9 035 $a(CKB)1000000000702638 035 $a(EBL)412763 035 $a(OCoLC)437089919 035 $a(SSID)ssj0000151272 035 $a(PQKBManifestationID)11910602 035 $a(PQKBTitleCode)TC0000151272 035 $a(PQKBWorkID)10282001 035 $a(PQKB)10965726 035 $a(UkCbUP)CR9780511759512 035 $a(MiAaPQ)EBC412763 035 $a(Au-PeEL)EBL412763 035 $a(CaPaEBR)ebr10277535 035 $a(CaONFJC)MIL200182 035 $a(EXLCZ)991000000000702638 100 $a20100430d2009|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEvidence-based diagnosis /$fThomas B. Newman, Michael A. Kohn$b[electronic resource] 210 1$aCambridge :$cCambridge University Press,$d2009. 215 $a1 online resource (xiii, 295 pages) $cdigital, PDF file(s) 225 1 $aPractical Guides to Biostatistics and Epidemiology 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-71402-8 311 $a0-521-88652-X 320 $aIncludes bibliographical references and index. 327 $aIntroduction: Understanding diagnosis and diagnostic testing -- Reliability and measurement error -- Dichotomous tests -- Multilevel and continuous tests -- Critical appraisal of studies of diagnostic tests -- Screening tests -- Prognostic tests and studies -- Multiple tests and multivariable decision rules -- Quantifying treatment effects using randomized trials -- Alternatives to randomized trials for estimating treatment effects -- Understanding P-values and confidence intervals -- Challenges for evidence-based diagnosis. 330 $aEvidence-Based Diagnosis explains diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although needing only a minimum of mathematics, the quantitative discussions in this book are deeper and more rigorous than in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. This book is a great choice for anyone looking to select, develop, or apply medical tests. Topics covered include: the diagnostic process; test reliability and accuracy; testing and treatment thresholds; critical appraisal of studies of diagnostic, screening and prognostic tests; test independence and methods of combining tests; quantifying treatment benefits using randomized trials and observational studies; Bayesian interpretation of P values and confidence intervals; challenges for evidence-based diagnosis; likelihood ratios and ROC curves. 410 0$aPractical Guides to Biostatistics and Epidemiology 606 $aDiagnosis 606 $aEvidence-based medicine 606 $aFunction tests (Medicine)$xEvaluation 606 $aDiagnosis$xResearch 615 0$aDiagnosis. 615 0$aEvidence-based medicine. 615 0$aFunction tests (Medicine)$xEvaluation. 615 0$aDiagnosis$xResearch. 676 $a616.07/5 700 $aNewman$b Thomas B.$0103620 702 $aKohn$b Michael A. 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910454633503321 996 $aEvidence-based diagnosis$92477574 997 $aUNINA LEADER 01728nam 22005775u 450 001 9910148817003321 005 20211006144819.0 010 $a9783318044195 010 $a3318044199 035 $a(CKB)3780000000102446 035 $a(OCoLC)1046109964 035 $a(SZ-BaSKA)219810 035 $a(MiAaPQ)EBC31866510 035 $a(Au-PeEL)EBL31866510 035 $a(EXLCZ)993780000000102446 100 $a20211006d1980 uy 0 101 0 $aeng 135 $aurunu||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCholera and Related Diarrheas : $eMolecular Aspects of a Global Health Problem 43rd Nobel Symposium, co-sponsored by WHO, Stockholm, August 1978 / $f editors, Ö. Ouchterlony, J. Holmgren 205 $a1st ed. 210 $aBasel : $cS. Karger, $d1980 215 $a1 online resource (XII + 252 pages) : $c 64 figures, 77 tables 311 08$a9783805530606 311 08$a3805530609 606 $aInfectious Diseases 606 $aAllergy 606 $aGastroenterology 606 $aImmunology 606 $aPreventive Medicine 606 $aSocial Medicine 615 14$aInfectious Diseases 615 14$aAllergy 615 14$aGastroenterology 615 14$aImmunology 615 24$aPreventive Medicine 615 24$aSocial Medicine 676 $a616.9/32 700 $aOuchterlony$b Ö 701 $aOuchterlony$b O?rjan$084473 701 $aHolmgren$b Jan$01231183 712 02$aNobelstiftelsen. 712 02$aWorld Health Organization. 801 0$bUKSKG 801 1$bUKSKG 906 $aBOOK 912 $a9910148817003321 996 $aCholera and Related Diarrheas$92858621 997 $aUNINA