LEADER 03292nam 22005413 450 001 9910148655103321 005 20241107094840.0 035 $a(CKB)3710000000918278 035 $a(MiAaPQ)EBC6042088 035 $a(Au-PeEL)EBL6042088 035 $a(OCoLC)1156168869 035 $a(ODN)ODN0002624835 035 $a(EXLCZ)993710000000918278 100 $a20210901d2016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOdessa Sea 205 $a1st ed. 210 $d2016 210 1$aEast Rutherford :$cPenguin Publishing Group,$d2016. 210 4$dİ2016. 215 $a1 online resource (404 pages) 225 1 $aDirk Pitt Adventure ;$vv.24 311 08$a0-399-57551-0 311 08$a0-399-57552-9 330 $a"Over the years, Dirk Pitt has always had a knack for finding trouble. This time, it has found him. The extraordinary new novel from the grand master of adventure and #1 New York Times-bestselling author. Pitt, the director of the National Underwater and Marine Agency, is on the Black Sea, helping to locate a lost Ottoman shipwreck, when he responds to an urgent Mayday - "Under attack!" - from a nearby freighter. But when he and his colleague Al Giordino arrive, there is nobody there. Just dead bodies, a smell of sulfur in the air, and, as Pitt and Giordino explore, a blast from the stern that scuttles the ship swiftly, almost taking them with it. The more the two of them search for the secret of the death ship, the deeper they descend into an extraordinary series of discoveries. A desperate attempt in 1917 to preserve the wealth and power of the Romanov Empire. A Cold War bomber lost with a deadly cargo. A brilliant developer of advanced drone technology on an unknown mission.Modern-day nuclear smugglers, determined Ukrainian rebels, a beautiful anti-terrorism agent from Europol - all will combine to present Pitt with the most dangerous challenge of his career. And not only Pitt. His two children, marine engineer Dirk and oceanographer Summer, are exploring a mysterious shipwreck of their own, when they are catapulted into his orbit. The three of them are used to perilous situations - but this time, they may have found their match. Filled with breathtaking suspense and remarkable imagination, Odessa Sea is further proof that when it comes to adventure writing, nobody beats Clive Cussler"--$cProvided by publisher. 330 $a"Pitt, the director of the National Underwater and Marine Agency, is on the Black Sea, helping to locate a lost Ottoman shipwreck, when he responds to an urgent Mayday - "Under attack!" - from a nearby freighter"--$cProvided by publisher. 410 0$aDirk Pitt Adventure 606 $aFiction$2OverDrive 606 $aSuspense$2OverDrive 606 $aThriller$2OverDrive 615 17$aFiction. 615 7$aSuspense. 615 7$aThriller. 676 $a813/.54 686 $aFIC002000$aFIC030000$aFIC031000$2bisacsh 700 $aCussler$b Clive$01242820 701 $aCussler$b Dirk$01245979 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910148655103321 996 $aOdessa Sea$92889286 997 $aUNINA LEADER 04445nam 22005655 450 001 9910298396203321 005 20251113181633.0 010 $a981-10-8417-3 024 7 $a10.1007/978-981-10-8417-1 035 $a(CKB)3850000000032870 035 $a(MiAaPQ)EBC5448124 035 $a(DE-He213)978-981-10-8417-1 035 $a(PPN)229499848 035 $a(EXLCZ)993850000000032870 100 $a20180703d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAnticancer Plants: Mechanisms and Molecular Interactions $eVolume 4 /$fedited by Mohd Sayeed Akhtar, Mallappa Kumara Swamy 205 $a1st ed. 2018. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2018. 215 $a1 online resource (365 pages) 311 08$a981-10-8416-5 327 $aChapter 1. Omics- a holistic approach in cancer treatment -- Chapter 2. Plant miRNAs and phytomolecules as anticancer therapeutics -- Chapter 3. Potential of herbal medicines in colorectal carcinoma and their mechanism of action -- Chapter 4. Elucidation of mechanisms of anticancer plant compounds against the tumor cells -- Chapter 5. Computational approach towards exploring interaction of target protein-phytocompounds in drug development for breast cancer -- Chapter 6. Anticancer Potential of Andrographolide, a diterpenoid lactone from Andrographis paniculata: A nature?s treasure for chemoprevention and therapeutics -- Chapter 7. Anticancer activity of herbal medicine: Mechanism of action -- Chapter 8. Metabolomic study of chemo-preventive phytochemicals and their therapeutic prospects -- Chapter 9. CADD studies applied to secondary metabolites in the anticancer drug research -- Chapter 10. Anticancerous plant compounds affecting the power house of cancerous cells: A possible herbal mitocan.-Chapter 11. Phytoestrogens as a natural source for the possible colon cancer treatment -- Chapter 12. Bioinformatics approaches for genomics and post genomics applications of anticancer plants -- Chapter 13. Fruits of Rosaceae family as a source of anticancer compounds and molecular innovations -- Chapter 14. Mechanism of action of anticancer herbal medicines. 330 $aThis book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breedingprograms to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. Thebook provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research. . 606 $aPlant physiology 606 $aProteins 606 $aAgriculture 606 $aPlant genetics 606 $aPlant Physiology 606 $aProtein Biochemistry 606 $aAgriculture 606 $aPlant Genetics 615 0$aPlant physiology. 615 0$aProteins. 615 0$aAgriculture. 615 0$aPlant genetics. 615 14$aPlant Physiology. 615 24$aProtein Biochemistry. 615 24$aAgriculture. 615 24$aPlant Genetics. 676 $a615.321 702 $aAkhtar$b Mohd. Sayeed$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKumara Swamy$b Mallappa$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298396203321 996 $aAnticancer Plants: Mechanisms and Molecular Interactions$92508880 997 $aUNINA