LEADER 04104nam 2200613 450 001 9910146746103321 005 20220505220123.0 010 $a3-540-74029-5 024 7 $a10.1007/978-3-540-74029-2 035 $a(CKB)1000000000492280 035 $a(SSID)ssj0000319888 035 $a(PQKBManifestationID)11233790 035 $a(PQKBTitleCode)TC0000319888 035 $a(PQKBWorkID)10338791 035 $a(PQKB)10418777 035 $a(DE-He213)978-3-540-74029-2 035 $a(MiAaPQ)EBC3062062 035 $a(MiAaPQ)EBC6705886 035 $a(Au-PeEL)EBL6705886 035 $a(PPN)123739411 035 $a(EXLCZ)991000000000492280 100 $a20220505d2008 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 00$aRugged free energy landscapes $ecommon computational approaches in spin glasses, structural glasses, and biological macromolecules /$fedited by W. Janke 205 $a1st ed. 2008. 210 1$aBerlin, Germany ;$aNew York, New York :$cSpringer,$d[2008] 210 4$dİ2008 215 $a1 online resource (X, 412 p.) 225 1 $aLecture Notes in Physics,$x0075-8450 ;$v736 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-540-74025-2 320 $aIncludes bibliographical references and index. 327 $aRugged Free-Energy Landscapes ? An Introduction -- Rugged Free-Energy Landscapes ? An Introduction -- Spin Glasses -- Some Aspects of Infinite-Range Models of Spin Glasses: Theory and Numerical Simulations -- The Potts Glass Model: A Scenario for the Freezing Transition of Structural Glasses? -- Domain Walls, Droplets and Barriers in Two-Dimensional Ising Spin Glasses -- Local Scale-Invariance in Disordered Systems -- Structural Glasses -- Transport of Mobile Particles in an Immobile Environment: Computer Simulations of Sodium Silicates -- The Gonihedric Ising Model and Glassiness -- Protein Folding -- Thermodynamics of Protein Folding from Coarse-Grained Models? Perspectives -- Exact Energy Landscapes of Proteins Using a Coarse-Grained Model -- Protein Folding, Unfolding and Aggregation Studied Using an All-Atom Model with~a~Simplified Interaction Potential -- All-Atom Simulations of Proteins -- Algorithmic Developments -- Markov Chain Monte Carlo Methods for Simulations of Biomolecules -- A Different Approach to Monte Carlo Simulations in Systems with Complex Free-Energy Landscapes -- Generalized-Ensemble Algorithms for Protein Folding Simulations. 330 $aThis collection of lectures and tutorial reviews by renowned experts focusses on the common computational approaches in use to unravel the static and dynamical behaviour of complex physical systems at the interface of physics, chemistry and biology. Paradigmatic examples of condensed matter physics are spin and structural glasses and protein folding, as well as their aggregation and adsorption to hard and soft surfaces, in physico-chemical biology. Among the most prominent joint key features of the systems considered in this volume are rugged free-energy landscapes. These generate metastability and are often responsible for very slow dynamics allowing for the system to be trapped in one of the many available local minima. The challenge set forth by the authors of this volume is to provide a common basis and technical language for the (computational) technology transfer between the fields and systems considered. 410 0$aLecture Notes in Physics,$x0075-8450 ;$v736 606 $aSpin glasses$xMathematical models 606 $aCondensed matter$xMathematical models 606 $aProtein folding$xMathematical models 615 0$aSpin glasses$xMathematical models. 615 0$aCondensed matter$xMathematical models. 615 0$aProtein folding$xMathematical models. 676 $a530.413 702 $aJanke$b W$g(Wolfhard), 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910146746103321 996 $aRugged free energy landscapes$91020982 997 $aUNINA