LEADER 04022oam 2200757zu 450 001 9910146088303321 005 20210721055552.0 010 $a1-280-55635-8 010 $a9786610556359 010 $a0-471-22395-6 035 $a(CKB)1000000000018924 035 $a(SSID)ssj0000310353 035 $a(PQKBManifestationID)11207137 035 $a(PQKBTitleCode)TC0000310353 035 $a(PQKBWorkID)10289797 035 $a(PQKB)10629844 035 $a(MiAaPQ)EBC4957583 035 $a(Au-PeEL)EBL4957583 035 $a(CaONFJC)MIL55635 035 $a(OCoLC)1024264655 035 $a(EXLCZ)991000000000018924 100 $a20160829d1998 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aStem cell biology and gene therapy 205 $aReissue 210 31$a[Place of publication not identified]$cWiley Liss$d1998 215 $a1 online resource (570 pages) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-471-14656-0 330 $aSTEM CELL BIOLOGY AND GENE THERAPY Edited by Peter J. Quesenberry, Gary S. Stein, Bernard Forget, and Sherman Weissman Advances in molecular genetics and recombinant DNA technology have ushered in a new era in medical therapeutic research. New insights into the molecular basis of human disease and the role played by biological regulatory mechanisms have precipitated tremendous drug development efforts backed by intensive research into human gene therapy worldwide. Stem Cell Biology and Gene Therapy is the first book to thoroughly cover major advances in the field and their applications to novel molecular therapies. This self-contained volume integrates biological and clinical components of stem cell biology, examines some of the most difficult aspects of gene therapy, and provides a systematic review of advanced gene modification techniques.; Twenty essays by leading researchers address some of the most compelling topics in contemporary medical research, including: Fundamental regulatory mechanisms that operate in stem cells Stem cells from a therapeutic perspective, including preparations of stem cells and their therapeutic potential as vehicles for gene therapy Delivery systems for therapeutic genes, including an overview of the most promising vectors Clinical applications for gene therapy, covering a broad range of diseases such as hemophilia, cancers, neurological disease, and more Complete with illustrations and real-world examples of a variety of disorders, Stem Cell Biology and Gene Therapy is essential for researchers in gene therapy and members of the biotechnology industry who are developing human molecular therapies for commercial use. It is also an important reference for molecular biologists, cell biologists, immunologists, molecular geneticists, hematologists, cancer researchers, biochemists, and anyone working in internal medicine. 606 $aGene therapy$xTherapeutic use 606 $aHematopoietic stem cells 606 $aHematopoietic Stem Cells 606 $aBone Marrow Cells 606 $aStem Cells 606 $aHematopoietic System 606 $aCells 606 $aAnatomy 606 $aHemic and Immune Systems 606 $aPathology$2HILCC 606 $aMedicine$2HILCC 606 $aHealth & Biological Sciences$2HILCC 608 $aElectronic books. 615 0$aGene therapy$xTherapeutic use 615 0$aHematopoietic stem cells 615 2$aHematopoietic Stem Cells 615 2$aBone Marrow Cells 615 2$aStem Cells 615 2$aHematopoietic System 615 2$aCells 615 2$aAnatomy 615 2$aHemic and Immune Systems 615 7$aPathology 615 7$aMedicine 615 7$aHealth & Biological Sciences 676 $a616/.042 702 $aQuesenberry$b Peter J 801 0$bPQKB 906 $aBOOK 912 $a9910146088303321 996 $aStem cell biology and gene therapy$92068021 997 $aUNINA