LEADER 03097oam 2200649zu 450 001 9910146052003321 005 20210721060846.0 010 $a1-280-64441-9 010 $a9786610644414 010 $a3-527-60006-X 035 $a(CKB)1000000000019250 035 $a(SSID)ssj0000294356 035 $a(PQKBManifestationID)11206505 035 $a(PQKBTitleCode)TC0000294356 035 $a(PQKBWorkID)10311941 035 $a(PQKB)11094841 035 $a(MiAaPQ)EBC5247793 035 $a(Au-PeEL)EBL5247793 035 $a(CaONFJC)MIL64441 035 $a(OCoLC)1027198693 035 $a(EXLCZ)991000000000019250 100 $a20160829d2001 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDrug targeting : organ-specific strategies 210 31$a[Place of publication not identified]$cWiley VCH$d2001 215 $a1 online resource (406 pages) 225 0 $aMethods and principles in medicinal chemistry Drug targeting 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-527-29989-0 330 $aHow are medicines transported intact through the body to their specific target sites without triggering side effects? The answer is "Drug Targeting". This thoroughly application--oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on the practical aspect and successful application of the method in question, although a glance at what the future holds is also included. 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Reverse osmosis is rapidly growing as a water treatment technology used for many applications, such as boiler feed water and recovering wastwater for reuse. This ""green"" technology is becoming more and more widely used in many settings, especially in industry. Even as the technology becomes more widespread, the understanding of the technology is lagging behind. 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