LEADER 01410nam 2200397 450 001 9910145875203321 005 20200324091709.0 035 $a(CKB)1000000000279564 035 $a(ItFiC)it 03252841 035 $a(EXLCZ)991000000000279564 100 $a20060828g20019999 uy 0 101 0 $aita 200 00$aAlle frontiere della vita$b[electronic resource] $eeutanasia ed etica del morire$hVolume 2. /$fa cura .di Marianna Gensabella Furnari ; contribuiti di S. Montanini [et al.] 210 $aSoveria Mannelli (Catanzaro) $cRubbettino$d2001- 215 $av 225 0$aSaggi 300 $aProceedings. 300 $aAlso cont. 1 text in English. 311 $a88-498-0582-9 320 $aIncludes bibliographical references. 327 $a2. : Atti del Convegno internazionale di studi, Messina, 13-14 novembre 2001 / a cura di Marianna Gensabella Furnari ; contributi di Salvatore Montanini ... [et al.]. - 2003. - 421 p. 606 $aEuthanasia$vCongresses 606 $aMedical ethics$vCongresses 606 $aRight to die$vCongresses 615 0$aEuthanasia 615 0$aMedical ethics 615 0$aRight to die 676 $a179 702 $aFurnari$b Marianna Genasabella 702 $aMontanini$b Salvatore 801 0$bItFiC 801 1$bItFiC 906 $aBOOK 912 $a9910145875203321 996 $aAlle frontiere della vita$92427004 997 $aUNINA LEADER 05168nam 2200661Ia 450 001 9910145254203321 005 20200520144314.0 010 $a9786612021640 010 $a9781282021648 010 $a1282021648 010 $a9783527626236 010 $a3527626239 010 $a9783527626243 010 $a3527626247 035 $a(CKB)1000000000707620 035 $a(EBL)481909 035 $a(SSID)ssj0000117859 035 $a(PQKBManifestationID)11143712 035 $a(PQKBTitleCode)TC0000117859 035 $a(PQKBWorkID)10049305 035 $a(PQKB)10690198 035 $a(MiAaPQ)EBC481909 035 $a(OCoLC)352832572 035 $a(Perlego)2753897 035 $a(EXLCZ)991000000000707620 100 $a20080402d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCardiovascular hormone systems /$fedited by Michael Bader 210 $aWeinheim $cWiley-VCH$dc2008 215 $a1 online resource (459 p.) 300 $aDescription based upon print version of record. 311 08$a9783527319206 311 08$a3527319204 320 $aIncludes bibliographical references and index. 327 $aCardiovascular Hormone Systems; Contents; Preface; List of Contributors; Part One: Steroid Hormones; 1: Glucocorticoids and Mineralocorticoids; 1.1 Synthesis of the Corticosteroids; 1.2 Regulation of Corticosteroid Synthesis; 1.2.1 Aldosterone; 1.2.2 Glucocorticoids; 1.3 Corticosteroid Receptors and Control of Ligand Access; 1.3.1 Steroid Receptors; 1.3.2 Control of Ligand Access; 1.3.2.1 11BHSD1; 1.3.2.2 11BHSD2; 1.4 Cardiovascular Effects of Aldosterone; 1.4.1 Aldosterone and the Heart; 1.4.2 Vasculature; 1.5 Cardiovascular Effects of Glucocorticoids; 1.5.1 Transgenic Models 327 $a1.5.2 Lessons from Human Disease1.5.2.1 Cushing's Syndrome; 1.5.2.2 The Metabolic Syndrome and Tissue-Specific Regulation of Glucocorticoids; 1.5.2.3 Glucocorticoid Resistance Syndrome; 1.5.2.4 GR Polymorphisms; 1.5.3 Endothelial Dysfunction, Vascular Tone and Atherosclerosis; References; 2: Sex Steroid Hormones; 2.1 Sex Differences in Cardiovascular Physiology and Disease and Effect of Hormone Therapy; 2.2 Sex Steroids: Estradiol, Estrone, Testosterone and Progesterone; 2.2.1 Synthesis and Endocrine Physiology; 2.2.2 Age-Dependent Blood Levels of Sex Hormones in Females and Males 327 $a2.2.3 Levels of Estradiol and Testosterone in Rodents2.3 Sex Hormone Receptors: Structure and Function; 2.3.1 Hormone Response Elements; 2.3.2 Molecular Mechanisms of Nuclear Receptor Activation; 2.3.2.1 Ligand-Dependent Transcription; 2.3.2.2 Ligand-Independent Genomic Pathway: Cross-Talk Between SHR s and Other Signal Transduction Pathways; 2.3.2.3 Nongenomic Pathway; 2.3.3 Role of Coregulators in Transcriptional Regulation by SHRs; 2.3.4 Role of Proteasomal Degradation Pathway in SHR-Mediated Gene Transcription; 2.3.5 Receptor Activity and Availability in the Cardiovascular System 327 $a2.3.6 Localization of SHRs in the Heart and Vessels of Rodent and Men2.4 Receptor-Independent Effects of Sex Steroids; 2.5 Sex Hormone Effects on Cardiovascular Cells and Organs; 2.5.1 Sex Hormone Effects on Different Cardiovascular Cell Types; 2.5.1.1 Cardiomyocytes; 2.5.1.2 Fibroblasts; 2.5.1.3 Endothelial Cells; 2.5.1.4 Vascular Smooth Muscle Cells; 2.5.1.5 Platelets; 2.5.2 Sex Hormone Effects on the Heart; 2.5.2.1 Effects of Exercise; 2.5.2.2 Pressure Overload; 2.5.2.3 Hypertension; 2.5.2.4 Volume Overload; 2.5.2.5 Myocardial Infarction 327 $a2.5.3 Sex Hormone Effects on Atherosclerosis, Plaque Formation and Rupture2.5.4 Sex Hormone Effects on Systemic and Circulating Mediators of the Cardiovascular System; 2.5.4.1 Lipid Levels; 2.5.4.2 Glucose and Insulin; 2.5.4.3 Blood Pressure; 2.5.4.4 Coagulatory Activity; References; Part Two: Peptide Hormones; 3: Angiotensins; 3.1 Introduction; 3.2 RAS: The Classical and Updated View; 3.3 New Aspects of Classical RAS Enzymes; 3.3.1 Renin/Prorenin Receptor; 3.3.2 Signaling Through ACE; 3.4 Ang II; 3.4.1 Ang II and the Cardiovascular System; 3.4.2 Ang II and the Endocrine System 327 $a3.4.3 Ang II and the Renal System 330 $aEdited by a renowned scientist in the field with more than 200 high profile scientific publications to his name, this is the first book to provide a comprehensive overview of all cardiovascular hormone systems. 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