LEADER 02530nam 2200601Ia 450 001 9910145688503321 005 20200520144314.0 010 $a9786611320898 010 $a9781281320896 010 $a1281320897 010 $a9780470757086 010 $a0470757086 010 $a9780470756843 010 $a0470756845 035 $a(CKB)1000000000415380 035 $a(EBL)351370 035 $a(OCoLC)298437981 035 $a(SSID)ssj0000227304 035 $a(PQKBManifestationID)11947088 035 $a(PQKBTitleCode)TC0000227304 035 $a(PQKBWorkID)10264590 035 $a(PQKB)11317128 035 $a(MiAaPQ)EBC351370 035 $a(Perlego)2773400 035 $a(EXLCZ)991000000000415380 100 $a20000620d2001 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aPrinciples of cell proliferation /$fJohn K. Heath 210 $aOxford ;$aMalden, MA $cBlackwell Science$d2001 215 $a1 online resource (150 p.) 300 $aDescription based upon print version of record. 311 08$a9780632048861 311 08$a0632048867 320 $aIncludes bibliographical references (p. 131-133) and index. 327 $aPrinciples of Cell Proliferation; Contents; Preface; Abbreviations; 1 Biology of the Cell Cycle; 2 Growth Factors; 3 Receptors; 4 Intracellular Signals; 5 Gene Expression; 6 The Cell Cycle Engine; 7 Oncogenes; 8 Tumour Suppressor Genes; 9 Cell Survival; Further Reading; Index 330 $aControlled expansion of cell populations is a fundamental feature of living organisms, being a finely-tuned balance between cell proliferation and cell death. This book aims to explain the molecular mechanisms that lie behind the multiplication and survival of eukaryotic cells. This encompasses both the normal regulation of cell populations in development or physiological adaptation and pathological mechanisms of cell cycle control in cancer. Principles of Cell Proliferation progressively introduces the function of growth factors, receptors, signal transduction pathways, gene expr 606 $aCarcinogenesis 606 $aCell proliferation 615 0$aCarcinogenesis. 615 0$aCell proliferation. 676 $a571.8/4 700 $aHeath$b J. K$0881321 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910145688503321 996 $aPrinciples of cell proliferation$91968250 997 $aUNINA