LEADER 05590nam 22006254a 450 001 9910830560303321 005 20230828212609.0 010 $a1-280-46840-8 010 $a9786610468409 010 $a0-470-03723-7 010 $a0-470-03722-9 035 $a(CKB)1000000000355057 035 $a(EBL)261336 035 $a(OCoLC)475976820 035 $a(SSID)ssj0000127775 035 $a(PQKBManifestationID)11148052 035 $a(PQKBTitleCode)TC0000127775 035 $a(PQKBWorkID)10052107 035 $a(PQKB)10597649 035 $a(MiAaPQ)EBC261336 035 $a(EXLCZ)991000000000355057 100 $a20051122d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aComputer applications in pharmaceutical research and development$b[electronic resource] /$f[edited by] Sean Ekins 210 $aHoboken, N.J. $cWiley-Interscience$dc2006 215 $a1 online resource (840 p.) 225 1 $aWiley series in drug discovery and development 300 $aDescription based upon print version of record. 311 $a0-471-73779-8 320 $aIncludes bibliographical references and index. 327 $aThe history of computers in pharmaceutical research and development: a narrative / Donald B. Boyd and Max M. Marsh -- Computers as data analysis and data management tools in preclinical development / Weiyong Li and Kenneth Banks -- Statistical modeling in pharmaceutical research and development / Andrea de Gaetano ... [et al.] -- Drug discovery from historic herbal texts / Eric J. Buenz -- Contextualizing the impact of bioinformatics on preclinical drug and vaccine discovery / Darren R. Flower -- Systems approaches for pharmaceutical research and development / Sean Ekins and Craig Giroux -- Information management-biodata in life sciences / Richard K. Scott and Anthony Parsons -- Chemoinformatics techniques for processing chemical structure databases / Valerie J. Gillet and Peter Willett -- Electronic laboratory notebooks / Alfred Nehme and Robert A. Scoffin -- Strategies for using information effectively in early-stage drug discovery / David J. Wild -- Improving the pharmaceutical R&D process: how simulation can support management decision making / Andrew Chadwick ... [et al.] -- 327 $aComputers and protein crystallography / David J. Edwards and Roderick E. Hubbard -- Computers, cheminformatics, and the medicinal chemist / Weifan Zheng and Michael Jones -- The challenges of making useful protein-ligand free energy predictions for drug discovery / Jun Shimada -- Computer algorithms for selecting molecule libraries for synthesis / Konstantin V. Balakin, Nikolay P. Savchuk, and Alex Kiselyov -- Success stories of computer-aided design / Hugo Kubinyi -- Pharmaceutical research and development productivity: can software help? / Christophe Lambert and S. Stanley Young -- Computer methods for predicting drug metabolism / Sean Ekins -- Computers in toxicology and risk assessment / John C. Dearden -- Computational modeling of drug disposition / Cheng Chang and Peter W. Swaan -- Computer simulations in pharmacokinetics and pharmacodynamics: rediscovering systems physiology in the 21st century / Paolo Vicini -- Predictive models for better decisions from understanding physiology to optimizing trial design / James R. Bosley, Jr -- 327 $aMaking pharmaceutical development more efficient / Michael Rosenberg and Richard Farris -- Use of interactive software in medical decision making / Rene?e J. Goldberg Arnold -- Clinical data collection and management / Mazen Abdellatif -- Regulation of computer systems / Sandy Weinberg -- A new paradigm for analyzing adverse drug events / Ana Szarfman, Jonathan G. Levine and Joseph M. Tonning -- Computers in pharmaceutical formulation / Raymond C. Rowe and Elizabeth A. Colbourn -- Legal protection of innovative uses of computers in R&D / Robert Harrison -- The ethics of computing in pharmaceutical research / Matthew K. McGowan and Richard J. McGowan -- The UltraLink: an expert system for contextual hyperlinking in knowledge management / Martin Romacker ... [et al.] -- Powerful, predictive and pervasive: the future of computers in the pharmaceutical industry / Nick Davies, Heather Ahlborn, Stuart Henderson. 330 $aA unique, holistic approach covering all functions and phases of pharmaceutical research and developmentWhile there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers read 410 0$aWiley series in drug discovery and development. 606 $aPharmacy$xData processing 606 $aPharmacology$xData processing 606 $aPharmaceutical industry$xData processing 615 0$aPharmacy$xData processing. 615 0$aPharmacology$xData processing. 615 0$aPharmaceutical industry$xData processing. 676 $a615.0285 676 $a615/.10285 701 $aEkins$b Sean$0927740 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830560303321 996 $aComputer applications in pharmaceutical research and development$93939271 997 $aUNINA LEADER 01752oam 2200493zu 450 001 9910145456203321 005 20241212215418.0 010 $a9781509099733 010 $a1509099735 035 $a(CKB)1000000000278035 035 $a(SSID)ssj0000396385 035 $a(PQKBManifestationID)12144216 035 $a(PQKBTitleCode)TC0000396385 035 $a(PQKBWorkID)10465008 035 $a(PQKB)11094832 035 $a(EXLCZ)991000000000278035 100 $a20160829d2005 uy 101 0 $aeng 181 $ctxt 182 $cc 183 $acr 200 10$aFirst International Workshop on Systematic Approaches to Digital Forensic Engineering : proceedings : 7-9 November 2005, Taipei, Taiwan 210 31$a[Place of publication not identified]$cIEEE Computer Society$d2005 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780769524788 311 08$a0769524788 606 $aDigital forensic science$vCongresses 606 $aForensic engineering$vCongresses 606 $aSocial Welfare & Social Work$2HILCC 606 $aSocial Sciences$2HILCC 606 $aCriminology, Penology & Juvenile Delinquency$2HILCC 615 0$aDigital forensic science 615 0$aForensic engineering 615 7$aSocial Welfare & Social Work 615 7$aSocial Sciences 615 7$aCriminology, Penology & Juvenile Delinquency 676 $a363.25/968 712 02$aChina (Republic : 1949- ) Jiao yu bu. 712 02$aGuo li Chenggong da xue, 801 0$bPQKB 906 $aPROCEEDING 912 $a9910145456203321 996 $aFirst International Workshop on Systematic Approaches to Digital Forensic Engineering : proceedings : 7-9 November 2005, Taipei, Taiwan$92419445 997 $aUNINA