LEADER 04425nam 2200649Ia 450 001 9910145440203321 005 20180612233952.0 010 $a1-281-06941-8 010 $a9786611069414 010 $a0-470-69232-4 010 $a0-470-76651-4 035 $a(CKB)1000000000402079 035 $a(EBL)320087 035 $a(OCoLC)476116586 035 $a(SSID)ssj0000176875 035 $a(PQKBManifestationID)11182948 035 $a(PQKBTitleCode)TC0000176875 035 $a(PQKBWorkID)10210099 035 $a(PQKB)10256053 035 $a(MiAaPQ)EBC320087 035 $a(EXLCZ)991000000000402079 100 $a20070829d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aImmune dysfunction and immunotherapy in heart disease$b[electronic resource] /$fedited by Ronald Ross Watson & Douglas F. Larson 210 $aOxford $cBlackwell$d2007 215 $a1 online resource (323 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-5568-X 320 $aIncludes bibliographical references and index. 327 $aImmune Dysfunction and Immunotherapy in Heart Disease; Contents; Contributors; Preface; About the Editors; Part I Immune dysfunction leading to heart disease: induction by physiological changes; 1 Immunosuppression by ultraviolet light-B radiation: a mediator of cardiac remodeling; 2 Immune mechanisms in pediatric cardiovascular disease; 3 Heart failure-role of autoimmunity; 4 Immune basis of hypertension in humans; 5 Immune dysregulation: potential mediator metabolic syndrome-induced cardiac remodeling; 6 T helper 2 cell cytokines in remodeling of aortic wall 327 $a7 Effects of TNF-a on cardiac function8 Immunosuppression in promotion of cardiac allograft vasculopathy; 9 Immunotherapy for left ventricular dysfunction after heart transplantation; Part II Immune dysfunction promoting CVD: induction by transplantation drugs; 10 Immunomodulating therapy in chronic heart failure; 11 Statins in atherosclerosis: role of immune regulation; 12 ACE inhibitors as immunomodulators: treatment of cardiovascular disease; 13 Treatment of heart failure by anticytokine therapies 327 $aPart III Immune dysfunction leading to heart dysfunction: induction or prevention by cardiotherapeutic drugs14 Pathogenesis of cardiovascular complications in the acquired immunodeficiency syndrome; 15 Cytokines and T cell-mediated responses in autoimmune myocarditis; 16 Drugs of abuse: accentuation of immunomodulation of viral myocarditis; Part IV Immune dysfunction leading to heart disease: induction by pathogens; 17 Osteopontin: the link between the immune system and cardiac remodeling; 18 Inflammatory immune activation in heart failure patients: therapeutic implications 327 $a26 Role of oral pathogens in the pathogenesis of coronary heart disease27 Myocardial regenerative potential by stem cell transplant; 28 Bioflavanoids and dietary anti-inflammatory actions: role in cardiovascular diseases; Index 330 $aCurrent heart failure therapeutics affects symptoms without appreciably reducing the mortality rate of 50% in five years -- suggesting a failure in treating the underlying mechanism. This book proposes a new mechanism for heart failure; immune mediated cardiac remodelling for cardiac dysfunction. The outstanding editor team of two internationally recognized immunologists -- Ronald Watson, who has studied heart disease in immune dysfunction for a decade and has a patent for an immunotherapy of heart disease by immune regulation, and Douglas Larson, whose experience in cardiac transplantat 606 $aHeart$xDiseases$xImmunological aspects 606 $aHeart$xDiseases$xImmunotherapy 606 $aImmunologic diseases$xComplications 608 $aElectronic books. 615 0$aHeart$xDiseases$xImmunological aspects. 615 0$aHeart$xDiseases$xImmunotherapy. 615 0$aImmunologic diseases$xComplications. 676 $a616.1/207 676 $a616.1207 686 $aYB 9022$2rvk 701 $aWatson$b Ronald R$g(Ronald Ross)$0872276 701 $aLarson$b Douglas F$0941282 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910145440203321 996 $aImmune dysfunction and immunotherapy in heart disease$92123134 997 $aUNINA