LEADER 04113nam 2200637 a 450 001 9910145416003321 005 20230721030930.0 010 $a1-281-23744-2 010 $a9786611237448 010 $a0-470-25344-4 010 $a0-470-25342-8 035 $a(CKB)1000000000406149 035 $a(EBL)333730 035 $a(SSID)ssj0000111881 035 $a(PQKBManifestationID)11128802 035 $a(PQKBTitleCode)TC0000111881 035 $a(PQKBWorkID)10080565 035 $a(PQKB)10262835 035 $a(Au-PeEL)EBL333730 035 $a(CaPaEBR)ebr10226758 035 $a(CaONFJC)MIL123744 035 $a(OCoLC)214281384 035 $a(MiAaPQ)EBC333730 035 $a(EXLCZ)991000000000406149 100 $a20070820d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBioinformatics algorithms$b[electronic resource] $etechniques and applications /$fedited by Ion I. Ma?ndoiu and Alexander Zelikovsky 210 $aHoboken, N.J. $cWiley-Interscience$dc2008 215 $a1 online resource (517 p.) 225 1 $aWiley series on bioinformatics 300 $aDescription based upon print version of record. 311 $a0-470-09773-6 320 $aIncludes bibliographical references and index. 327 $aBIOINFORMATICS ALGORITHMS; CONTENTS; Preface; Contributors; 1 Educating Biologists in the 21st Century: Bioinformatics Scientists versus Bioinformatics Technicians; PART I TECHNIQUES; 2 Dynamic Programming Algorithms for Biological Sequence and Structure Comparison; 3 Graph Theoretical Approaches to Delineate Dynamics of Biological Processes; 4 Advances in Hidden Markov Models for Sequence Annotation; 5 Sorting- and FFT-Based Techniques in the Discovery of Biopatterns; 6 A Survey of Seeding for Sequence Alignment; 7 The Comparison of Phylogenetic Networks: Algorithms and Complexity 327 $aPART II GENOME AND SEQUENCE ANALYSIS8 Formal Models of Gene Clusters; 9 Integer Linear Programming Techniques for Discovering Approximate Gene Clusters; 10 Efficient Combinatorial Algorithms for DNA Sequence Processing; 11 Algorithms for Multiplex PCR Primer Set Selection with Amplification Length Constraints; 12 Recent Developments in Alignment and Motif Finding for Sequences and Networks; PART III MICROARRAY DESIGN AND DATA ANALYSIS; 13 Algorithms for Oligonucleotide Microarray Layout; 14 Classification Accuracy Based Microarray Missing Value Imputation; 15 Meta-Analysis of Microarray Data 327 $aPART IV GENETIC VARIATION ANALYSIS16 Phasing Genotypes Using a Hidden Markov Model; 17 Analytical and Algorithmic Methods for Haplotype Frequency Inference: What Do They Tell Us?; 18 Optimization Methods for Genotype Data Analysis in Epidemiological Studies; PART V STRUCTURAL AND SYSTEMS BIOLOGY; 19 Topological Indices in Combinatorial Chemistry; 20 Efficient Algorithms for Structural Recall in Databases; 21 Computational Approaches to Predict Protein-Protein and Domain-Domain Interactions; Index 330 $aPresents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers: General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, se 410 0$aWiley series on bioinformatics. 606 $aBioinformatics 606 $aAlgorithms 615 0$aBioinformatics. 615 0$aAlgorithms. 676 $a572.80285 701 $aMa?ndoiu$b Ion$0856333 701 $aZelikovsky$b Alexander$0919949 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910145416003321 996 $aBioinformatics algorithms$92063415 997 $aUNINA