LEADER 03362nam  2200601Ia 450 
001 9910145307603321
005 20170815113959.0
010   $a1-281-13540-2
010   $a9786611135409
010   $a0-470-72520-6
010   $a0-470-72519-2
035   $a(CKB)1000000000403146
035   $a(EBL)326422
035   $a(OCoLC)476124215
035   $a(SSID)ssj0000203681
035   $a(PQKBManifestationID)11168935
035   $a(PQKBTitleCode)TC0000203681
035   $a(PQKBWorkID)10174440
035   $a(PQKB)11175449
035   $a(MiAaPQ)EBC326422
035   $a(EXLCZ)991000000000403146
100   $a20080205d2007      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aMitochondrial biology$b[electronic resource] $enew perspectives /$f[editors: Derek J. Chadwick and Jamie Goode]
210   $aLondon $cJohn Wiley$d2007
215   $a1 online resource (255 p.)
225 1 $aNovartis Foundation symposium ;$v287
300   $aDescription based upon print version of record.
311   $a0-470-06657-1 
320   $aIncludes bibliographical references and index.
327   $aMITOCHONDRIAL BIOLOGY: NEW PERSPECTIVES; Contents; Chair's introduction; Outer mitochondrial membrane protein degradation by the proteasome; DISCUSSION; PA-GFP: a window into the subcellular adventures of the individual mitochondrion; DISCUSSION; Multiple functions of mitochondria-shaping proteins; DISCUSSION; Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators; DISCUSSION; Novel uncoupling proteins; DISCUSSION; Mitochondria as generators and targets of nitric oxide; DISCUSSION; Calcium signalling and mitochondrial motility; DISCUSSION
327   $aEndoplasmic reticulum/mitochondria calcium cross-talkDISCUSSION; Mitochondrial ion channels in cardiac function and dysfunction; DISCUSSION; The mitochondrial permeability transition pore; DISCUSSION; Mechanisms of mitochondrial outer membrane permeabilization; DISCUSSION; Mitochondria and neurodegeneration; DISCUSSION; Mitochondrial dysfunction in mammalian ageing; DISCUSSION; Mitochondrial mutations: genotype to phenotype; DISCUSSION; Contributor Index; Subject Index
330   $aWith the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial research. The book opens with the regulation of mitochondrial replication and biogenesis and reviews the mechanisms and functional consequences of mitochondrial fission and fusion. Further chapters address mitochondria and oxidative stress and their roles in cell signalling and cell death. The book includes extensive, fascinating discussion of the biochemistry of mitochondrial cell signalling (especi
410  0$aNovartis Foundation symposium ;$v287.
606   $aMitochondria
606   $aCell membranes
608   $aElectronic books.
615  0$aMitochondria.
615  0$aCell membranes.
676   $a571.657
701   $aChadwick$b Derek$091632
701   $aGoode$b Jamie$0283336
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910145307603321
996   $aMitochondrial biology$92131320
997   $aUNINA