LEADER 05184nam 2200649Ia 450 001 9910145263103321 005 20170809170313.0 010 $a1-282-02535-X 010 $a9786612025358 010 $a3-527-62617-4 010 $a3-527-62618-2 035 $a(CKB)1000000000707185 035 $a(EBL)481835 035 $a(OCoLC)352789988 035 $a(SSID)ssj0000225331 035 $a(PQKBManifestationID)11197655 035 $a(PQKBTitleCode)TC0000225331 035 $a(PQKBWorkID)10230334 035 $a(PQKB)10174231 035 $a(MiAaPQ)EBC481835 035 $a(EXLCZ)991000000000707185 100 $a20080227d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe power of functional resins in organic synthesis$b[electronic resource] /$fedited by Judit Tulla-Puche and Fernando Albericio 210 $aWeinheim $cWiley-VCH$dc2008 215 $a1 online resource (685 p.) 300 $aDescription based upon print version of record. 311 $a3-527-31936-0 320 $aIncludes bibliographical references and index. 327 $aThe Power of Functional Resins in Organic Synthesis; Contents; Preface; Part One: Introduction; 1: The (Classic Concept of) Solid Support; 1.1 Introduction; 1.2 Linkers/Handles; 1.3 Solid Supports; 1.3.1 Gel-Type Support; 1.3.1.1 Polystyrene (PS) Resins; 1.3.1.2 Poly(Ethylene Glycol)-Polystyrene (PEG-PS) Resins; 1.3.1.3 Hydrophilic PEG-Based Resins; 1.3.2 Modified Surface Type Supports; 1.3.2.1 Cellulose Membranes; 1.3.2.2 Polyolefinic Membranes; 1.3.2.3 Pellicular Solid Supports; Acknowledgments; References; 2: Molecularly Imprinted Polymers; 2.1 Introduction 327 $a2.2 The Concept of Molecular Imprinting2.2.1 Non-covalent Molecular Imprinting; 2.2.2 Covalent Molecular Imprinting; 2.2.3 Semi-covalent Molecular Imprinting; 2.2.4 Metal Ion Mediated Molecular Imprinting; 2.3 Formats of Molecularly Imprinted Polymers; 2.3.1 Irregularly Shaped Particles; 2.3.2 Beads; 2.3.2.1 Homogeneous Polymerization; 2.3.2.2 Heterogeneous Polymerization; 2.3.2.3 Two-Step Swelling Polymerization; 2.3.2.4 Core-Shell Polymerization; 2.3.2.5 Silica Composite Beads; 2.3.3 Films and Membranes; 2.4 Design of MIPs; 2.4.1 Functional Monomers; 2.4.2 Cross-linking Monomers 327 $a2.4.3 The Porogen2.4.4 Initiation of Polymerization; 2.4.5 Optimization of Imprinting Conditions; 2.5 Characterization of Molecularly Imprinted Polymers; 2.5.1 Characterization of Binding Properties of MIPs; 2.5.2 Characterization of Chemical and Physical Properties of MIPs; 2.6 Applications of Molecularly Imprinted Polymers; 2.6.1 Liquid Chromatography; 2.6.2 Solid-Phase Extraction; 2.6.3 Solid-Phase Binding Assay; 2.6.4 Sensors; 2.6.4.1 Optical Sensors; 2.6.4.2 Mass Sensitive Sensors; 2.6.4.3 Electrochemical Sensors; 2.6.5 Synthetic Enzymes; 2.7 Conclusions; References 327 $a3: Nanoparticles Functionalized with Bioactive Molecules: Biomedical Applications3.1 Introduction; 3.2 MNPs; 3.2.1 Gold Nanoparticles; 3.2.1.1 Synthesis and Properties; 3.2.1.2 Functionalization of GNPs with Bioactive Compounds and Biomedical Applications of Functionalized GNPs; 3.2.2 Nanoshells and Metal Heterodimers; 3.2.3 Iron Oxide NPs; 3.2.3.1 Synthesis and Properties; 3.2.3.2 Functionalization of IONPs; 3.2.4 Silver NPs; 3.2.5 Quantum Dots; 3.2.6 Nanowires; 3.3 CNTs; 3.4 Organic Nanoparticles (ONPs); 3.4.1 Synthesis and Properties of ONPs; 3.4.2 Functionalization Strategies 327 $a3.4.3 ONPs Types and Applications3.4.3.1 Fluorescent ONPs; 3.4.3.2 Cancer-Aimed ONPs; 3.4.3.3 Delivery of ONPs through the Blood-Brain Barrier (BBB); 3.4.3.4 Nucleic Acids/Gene Delivery; 3.4.3.5 Other Biomedical Uses of ONPs; 3.5 Conclusions; Acknowledgments; List of Abbreviations; References; Part Two: Solid-Supported Reagents and Scavengers; 4: Oxidizing and Reducing Agents; 4.1 Introduction; 4.2 Considerations Concerning the Nature of the Solid Support Used for Polymer-Supported Redox Reagents; 4.3 Oxidizing Resins; 4.3.1 Novel Oxidative Resins 327 $a4.3.1.1 Solid-Supported Hypervalent Iodine Reagents 330 $aWhile many books cover solid phase synthesis and combinatorial synthesis, this one is unique in its exclusive coverage of the other aspects of solid-phase synthesis. As such, it contains everything you need to know -- from supported reagents, to scavengers, resins, and the synthesis of biomolecules and natural products.An invaluable companion for all chemists and biochemists working in university research and industry. 606 $aGums and resins, Synthetic 606 $aOrganic compounds$xSynthesis 608 $aElectronic books. 615 0$aGums and resins, Synthetic. 615 0$aOrganic compounds$xSynthesis. 676 $a547.2 686 $a540$2sdnb 686 $aVK 5500$2rvk 701 $aAlbericio$b Fernando$0555734 701 $aTulla-Puche$b Judit$0980920 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910145263103321 996 $aThe power of functional resins in organic synthesis$92238529 997 $aUNINA