LEADER 02739nam 22005534a 450 001 9910145043303321 005 20180718182643.0 010 $a1-280-27566-9 010 $a9786610275663 010 $a0-470-01299-4 010 $a0-470-01298-6 035 $a(CKB)1000000000239297 035 $a(EBL)232675 035 $a(OCoLC)224426090 035 $a(SSID)ssj0000137284 035 $a(PQKBManifestationID)11954164 035 $a(PQKBTitleCode)TC0000137284 035 $a(PQKBWorkID)10088011 035 $a(PQKB)11232486 035 $a(MiAaPQ)EBC232675 035 $a(EXLCZ)991000000000239297 100 $a20041130d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aDesign of studies for medical research$b[electronic resource] /$fDavid Machlin, Michael J. Campbell 210 $aHoboken, NJ $cWiley$dc2005 215 $a1 online resource (286 p.) 300 $aDescription based upon print version of record. 311 $a0-470-84495-7 320 $aIncludes bibliographical references (p. [246]-254) and index. 327 $aDesign of Studies for Medical Research; Contents; Preface; Chapter 1 What is Evidence?; Chapter 2 Measurement, Forms and Questionnaires; Chapter 3 Principles of Study Size Calculation; Chapter 4 Randomisation; Chapter 5 Cross-sectional and Longitudinal Studies; Chapter 6 Surveys, Cohort and Case-Control Studies; Chapter 7 Clinical Trials - General Issues; Chapter 8 Early Clinical Trials; Chapter 9 Phase III Trials; Chapter 10 Diagnosis; Chapter 11 Prognostic Factor Studies; References; Tables; Index 330 $aThe same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development. With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design. This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples f 606 $aMedicine$xResearch$xMethodology 608 $aElectronic books. 615 0$aMedicine$xResearch$xMethodology. 676 $a610.72 676 $a610/.72 700 $aMachin$b David$f1939-$0520765 701 $aCampbell$b Michael J$0125733 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910145043303321 996 $aDesign of studies for medical research$91972667 997 $aUNINA