LEADER 04149nam 2200733 a 450 001 9910144742303321 005 20190522005435.0 010 $a1-282-34787-X 010 $a9786612347870 010 $a0-470-51451-5 010 $a0-470-51452-3 035 $a(CKB)1000000000377212 035 $a(EBL)470631 035 $a(OCoLC)609849612 035 $a(SSID)ssj0000303497 035 $a(PQKBManifestationID)11241697 035 $a(PQKBTitleCode)TC0000303497 035 $a(PQKBWorkID)10276333 035 $a(PQKB)10376193 035 $a(MiAaPQ)EBC470631 035 $a(EXLCZ)991000000000377212 100 $a19930716d1993 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe Molecular basis of smell and taste transduction$b[electronic resource] /$f[editors, Derek Chadwick, Joan Marsh, and Jamie Goode] 210 $aChichester ;$aNew York $cWiley$d1993 215 $a1 online resource (304 p.) 225 1 $aCiba Foundation symposium ;$v179 300 $a"A Wiley-Interscience publication." 300 $aSymposium on the Molecular Basis of Smell and Taste Transduction, held at the Ciba Foundation, London, Feb. 1993. 311 $a0-471-93946-3 320 $aIncludes bibliographical references and indexes. 327 $aTHE MOLECULAR BASIS OF SMELL AND TASTE TRANSDUCTION; Contents; Participants; Introduction; From genotype to olfactory neuron phenotype: the role of the Olf-I-binding site; Mucous domains: microchemical heterogeneity in the mucociliary complex of the olfactory epithelium; Receptor diversity and spatial patterning in the mammalian olfactory system; Molecular mechanisms of olfactory neuronal gene regulation; A new tool for investigating G protein-coupled receptors; General discussion I; Second messenger signalling in olfaction; Membrane currents and mechanisms of olfactory transduction 327 $aOlfactory receptors: transduction, diversity, human psychophysics and genome analysisGeneral discussion II; MolecuIar genetics of Drosophila olfaction; Perireceptor events in taste; Gustducin and transduci n: a tale of two G proteins; Role of apical ion channels in sour taste t ransduction; Ion pathways in the taste bud and their significance for transduction; The cellular and genetic basis of olfactory responses in Caenorhabditis elegans; Genetic and pathological taste variation: what can we learn from animal models and human disease?; General discussion Ill; Summing-up 327 $aIndex of contributorsSubject Index 330 $aRecent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the latest results are presented and discussed by leading scientists. The extensive coverage encompasses many important topics, including mucous domains; microchemical heterogeneity in the mucociliary complex of the olfactory epithelium; membrane currents and mechanisms of olfactory transduction, and genetic and pathological taste variation. 410 0$aCiba Foundation symposium ;$v179. 606 $aSmell$xMolecular aspects$vCongresses 606 $aTaste$xMolecular aspects$vCongresses 606 $aCellular signal transduction$vCongresses 606 $aSecond messengers (Biochemistry)$vCongresses 606 $aG proteins$vCongresses 608 $aElectronic books. 615 0$aSmell$xMolecular aspects 615 0$aTaste$xMolecular aspects 615 0$aCellular signal transduction 615 0$aSecond messengers (Biochemistry) 615 0$aG proteins 676 $a591.1 676 $a591.1826 701 $aChadwick$b Derek$091632 701 $aMarsh$b Joan$091633 701 $aGoode$b Jamie$0283336 712 12$aSymposium on the Molecular Basis of Smell and Taste Transduction$f(1993 :$eLondon, England) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144742303321 996 $aThe Molecular basis of smell and taste transduction$91954853 997 $aUNINA