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010   $a9786612346002
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035   $a(OCoLC)609849686
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100   $a19870402d1987      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aAutoimmunity and autoimmune disease$b[electronic resource]
210   $aChichester ;$aNew York $cWiley$d1987
215   $a1 online resource (290 p.)
225 1 $aCiba Foundation symposium ;$v129
300   $aEditors: David Evered (organizer) and Julie Whelan.
300   $a"Symposium on Autoimmunity and Autoimmune Disease, held at the Ciba Foundation, London, 30 September-2 October 1986"--Contents p.
300   $a"A Wiley-Interscience publication."
311   $a0-471-91095-3 
320   $aIncludes bibliographical references and indexes.
327   $aAUTOIMMUNITY AND AUTOIMMUNE DISEASE; Contents; Participants; Introduction; Cardiac myosin and autoimmune myocarditis; Intracellular autoantigens: diagnostic fingerprints but aetiological dilemmas; Significance of carbohydrate components of cell surfaces; How is tolerance generated?; Therapeutic immune regulation in experimental interstitial nephritis with suppressor T cells and their soluble factors; Regulation of HL4 class II expression and its role in autoimmune disease; Id iotypes and autoimmunity
327   $aMolecular basis for the cross-reactive idiotypes on human anti-lgG autoanti bodies (rheumatoid factors)Autoimmunity and immunodeficiency disease; Deficiency of the effector mechanisms of the immune response and au toimmu n ity; General discussion; Monoclonal anti-la antibody therapy in animal models of autoimmune disease; Monoclonal antibodies for the depletion of specific subpopulations of lymphocytes; Manipulation of idiotype networks in autoimmunity; Interferons: cytokines in autoimmunity; Specific immunoabsorption; Final general discussion; Chairman's summing-up; Index of contributors
327   $aSubject Index
330   $aThis work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research and
410  0$aCiba Foundation symposium ;$v129.
606   $aAutoimmune diseases$vCongresses
608   $aElectronic books.
615  0$aAutoimmune diseases
676   $a616.9
676   $a616.978
701   $aEvered$b David$0857127
701   $aWhelan$b Julie$0322651
712 12$aSymposium on Autoimmunity and Autoimmune Disease$f(1986 :$eCiba Foundation)
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910144737103321
996   $aAutoimmunity and autoimmune disease$92058851
997   $aUNINA