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100   $a19890925d1989      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aIgE, mast cells, and the allergic response$b[electronic resource]
210   $aChichester ;$aNew York $cJohn Wiley & Sons$d1989
215   $a1 online resource (294 p.)
225 1 $aCiba Foundation symposium ;$v147
300   $a"Symposium on IgE, Mast Cells, and the Allergic Response, held at the Ciba Foundation, London, 11-13 April 1989"--Contents p.
300   $aEdited and organized by Derek Chadwick and others.
300   $a"A Wiley-Interscience publication."
311   $a0-471-92309-5 
320   $aIncludes bibliographical references and indexes.
327   $aIgE, MAST CELLS AND THE ALLERGIC RESPONSE; Contents; Introduction; Control of in vivo IgE production in the mouse by interleukin 4; Structure and function of FcE receptor II (FcE,RII/CD23): a point of contact between the effector phase of allergy and B cell differentiation; Different mast cell mediators produced by different mast cell phenotypes; Mast cells: immunologically specific effectors and potential sources of multiple cytokines during IgE-dependent responses; Non-IgE-mediated mast cell stimulation; The receptor with high affinity for IgE
327   $aCalcium: an important second messenger in mast cellsLow affinity IgE receptors: regulation and functional roles in cell activation; IgE and inflammatory cells; Molecular genetics of human responsiveness to allergens; Influence of environmental factors on IgE production; Epidemiology of the allergic response; Heterogeneity of human FcERI-bearing cells; Conventional and new approaches to hyposensitization; Final general discussion; Closing statement; Index of contributors; Subject index
330   $aReviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the IgE field for its breadth of coverage and interdisciplinary nature, and it shows the benefits from the current rapid expansion of knowledge in cell biology, immunology, and molecular genetics, as well as the potential clinical significance of this research to clinical immunologists and allergologists.
410  0$aCiba Foundation symposium ;$v147.
606   $aImmunoglobulin E$vCongresses
606   $aMast cells$xImmunology$vCongresses
606   $aAllergy$xPathogenesis$vCongresses
608   $aElectronic books.
615  0$aImmunoglobulin E
615  0$aMast cells$xImmunology
615  0$aAllergy$xPathogenesis
676   $a599.0293
676   $a616.07
676   $a616.079
701   $aChadwick$b Derek$091632
712 12$aSymposium on IgE, Mast Cells and the Allergic Response$f(1989 :$eCiba Foundation)
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910144736803321
996   $aIgE, mast cells, and the allergic response$91954852
997   $aUNINA