LEADER 02617nam 22006133u 450 001 9910456488903321 005 20210111125404.0 010 $a0-8166-7688-7 035 $a(CKB)2550000000039600 035 $a(EBL)718864 035 $a(OCoLC)733040277 035 $a(SSID)ssj0000538098 035 $a(PQKBManifestationID)11335187 035 $a(PQKBTitleCode)TC0000538098 035 $a(PQKBWorkID)10557492 035 $a(PQKB)10047815 035 $a(MiAaPQ)EBC718864 035 $a(EXLCZ)992550000000039600 100 $a20130418d2011|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe Invisible Element of Place$b[electronic resource] $eThe Architecture of David Salmela 210 $aMinneapolis $cUniversity of Minnesota Press$d2011 215 $a1 online resource (259 p.) 300 $aDescription based upon print version of record. 311 $a0-8166-6994-5 327 $aCover; Contents; Introduction: The Invisible Made Visible; BOXES; GABLES; WINDBREAKS; SHEDS; CLUSTERS; Awards; Building Credits 330 $a""Even though it's bold, it doesn't shout at you,"" David Salmela says of the silvery house he designed for a woodsy setting in Deephaven, Minnesota. ""It's not a barking dog. It's a resting, very gentle animal."" The American Institute of Architects, conferring its 2008 Housing Award, was more direct: the house was, in the words of the jury, ""brilliantly designed."" The Streeter house is just one of fifty-one notable projects by Minnesota architect Salmela featured in ""The Invisible Element of Place."". Thomas Fisher explores both the beauty and the practicality of Salmela's award-winning d 606 $aArchitect-designed houses 606 $aSalmela, David -- Catalogs 606 $aSalmela, David -- Criticism and interpretation 606 $aArchitect-designed houses 606 $aArt, Architecture & Applied Arts$2HILCC 606 $aArchitecture$2HILCC 608 $aElectronic books. 615 4$aArchitect-designed houses. 615 4$aSalmela, David -- Catalogs. 615 4$aSalmela, David -- Criticism and interpretation. 615 0$aArchitect-designed houses 615 7$aArt, Architecture & Applied Arts 615 7$aArchitecture 676 $a720.92 700 $aFisher$b Thomas$0857234 701 $aBastianelli-Kerze$b Peter$0857235 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910456488903321 996 $aThe Invisible Element of Place$91914171 997 $aUNINA LEADER 05288nam 22006494a 450 001 9910144698903321 005 20200701130723.0 010 $a1-119-96561-6 010 $a1-282-34292-4 010 $a9786612342929 010 $a0-470-72572-9 010 $a0-470-72571-0 035 $a(CKB)1000000000687510 035 $a(EBL)470121 035 $a(OCoLC)648759868 035 $a(SSID)ssj0000303507 035 $a(PQKBManifestationID)11227118 035 $a(PQKBTitleCode)TC0000303507 035 $a(PQKBWorkID)10276610 035 $a(PQKB)11468947 035 $a(MiAaPQ)EBC470121 035 $a(EXLCZ)991000000000687510 100 $a20080125d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMolecular epidemiology of chronic diseases$b[electronic resource] /$feditors, Chris Wild, Paolo Vineis, Seymour Garte 210 $aChichester, England ;$aHoboken, NJ $cJ. Wiley$d2008 215 $a1 online resource (386 p.) 300 $aDescription based upon print version of record. 311 $a0-470-02743-6 320 $aIncludes bibliographical references and index. 327 $aMOLECULAR EPIDEMIOLOGY OF CHRONICDISEASES; Contents; Contributors; Acknowledgements; 1 Introduction: why molecular epidemiology?; 2 Study design; 2.1. Introduction: study design at square one; 2.2. Epidemiological measures; 2.3. Bias; 2.4. More on confounding; 2.5. Specifi cities of molecular epidemiology design; 2.6. Conclusions; References; Essential reading; 3 Molecular epidemiological studies that can be nested within cohorts; 3.1. Introduction; 3.2. Case-cohort studies; 3.3. Nested case-control studies 327 $a3.4. Considerations regarding biomarker analyses in case-cohort and nested case-control studies3.5. Conclusion; References; 4 Family studies, haplotypes and gene association studies; 4.1. Introduction; 4.2. Family studies; 4.3. Genetic association studies; 4.4. Discussion; References; 5 Individual susceptibility and gene-environment interaction; 5.1. Individual susceptibility; 5.2. Genetic susceptibility; 5.3. Metabolic susceptibility genes; 5.4. Study designs; 5.5. Gene-environment interaction; 5.6. Exposure dose effects in gene-environment interactions 327 $a5.7. Mutational effects of gene-environment interactions5.8. Conclusions; References; 6 Biomarker validation; 6.1. Validity and reliability; 6.2. Biomarker variability; 6.3. Measurement of variation; 6.4. Other issues of validation; 6.5. Measurement error; 6.6. Blood collection for biomarkers; 6.7. Validation of high-throughput techniques; References; 7 Exposure assessment; 7.1. Introduction; 7.2. Initial considerations of an exposure assessment strategy; 7.3. Exposure pathways and routes; 7.4. Exposure dimensions; 7.5. Exposure classifi cation, measurement or modelling 327 $a7.6. Retrospective exposure assessment7.7. Validation studies; 7.8. Quality control issues; References; 8 Carcinogen metabolites as biomarkers; 8.1. Introduction; 8.2. Overview of carcinogen metabolism; 8.3. Examples of carcinogen metabolite biomarkers; 8.4. Summary; References; 9 Biomarkers of exposure: adducts; 9.1. Introduction; 9.2. Methods for adduct detection; 9.3. Adducts identifi ed in human tissue; 9.4. Adducts as biomarkers of occupational and environmental exposure to carcinogens; 9.5. Smoking-related adducts; 9.6. DNA adducts in prospective studies; 9.7. Conclusions; References 327 $a10 Biomarkers of mutation and DNA repair capacity10.1. Introduction; 10.2. Classifi cation of mutations; 10.3. Mutations in molecular epidemiology; 10.4. DNA repair; 10.5. Classes of DNA repair; 10.6. Common assays to measure DNA repair capacity; 10.7. Integration of DNA repair assays into epidemiological studies; 10.8. Genetic markers for DNA repair capacity; References; 11 High-throughput techniques - genotyping and genomics; 11.1. Introduction; 11.2. Background; 11.3. SNP databases; 11.4. Study types; 11.5. Study design; 11.6. Genotyping technologies 327 $a11.7. Sample and study management and QC 330 $a""I think this is an excellent book-I recommend it to anyone involved in molecular epidemiology... The 26 chapters are written by topic specialists, in an explanatory, east to read style."" -BTS Newsletter, Summer 2009 ""This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiol 606 $aMolecular epidemiology 606 $aChronic diseases$xEpidemiology 608 $aElectronic books. 615 0$aMolecular epidemiology. 615 0$aChronic diseases$xEpidemiology. 676 $a614.4 701 $aWild$b Chris$f1959-$0983990 701 $aVineis$b Paolo$0451157 701 $aGarte$b Seymour J$0983991 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144698903321 996 $aMolecular epidemiology of chronic diseases$92246798 997 $aUNINA