LEADER 03741nam 2200673 a 450 001 9910144664303321 005 20230213211634.0 010 $a1-280-78418-0 010 $a9786613694577 010 $a0-470-72097-2 010 $a0-470-71867-6 035 $a(CKB)1000000000688055 035 $a(EBL)703936 035 $a(OCoLC)797918543 035 $a(SSID)ssj0000715056 035 $a(PQKBManifestationID)11394642 035 $a(PQKBTitleCode)TC0000715056 035 $a(PQKBWorkID)10678041 035 $a(PQKB)11131529 035 $a(MiAaPQ)EBC703936 035 $a(Au-PeEL)EBL703936 035 $a(CaPaEBR)ebr10575528 035 $a(CaONFJC)MIL369457 035 $a(EXLCZ)991000000000688055 100 $a19880825d1985 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGrowth factors in biology and medicine$b[electronic resource] /$f[editors, David Evered, Jonathan Nugent, and Julie Whelan.] 210 $aLondon $cPitman Pub.$d1985 215 $a1 online resource (296 p.) 225 1 $aCiba Foundation symposium ;$v116 300 $a"Symposium on Growth Factors in Biology and Medicine, held at the Ciba Foundation, London, 22-24 January, 1985"--Contents page. 311 $a0-470-66444-4 311 $a0-272-79818-5 320 $aIncludes bibliographical references and indexes. 327 $aGrowth factors in biology and medicine; Contents; Introduction; Growth factors in mammalian embryogen-esis; Discussion; The EGF receptor kinase: evidence for allos- teric activation and intramolecular self-phosphorylation; Discussion; Role of growth factors in oncogenesis: growth factor-proto-oncogene pathways of mitogenesis; Discussion; Signalling mitogene- sis in 3T3 cells: role of Ca*+-sensitive, phospholipid-dependent protein kinase; Discussion; The PDGF-inducible 'compe- tence genes': intracellular mediators of the mitogenic response; Discussion 327 $aPlatelet-derived growth factor: its potential roles in wound-healing, atherosclerosis, neoplasia, and growth and developmentDiscussion; Nerve growth factor; Discussion; The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells; Discussion; Haemopoietic growth factors: structure and receptor interac- tions; Discussion; In vivo effects of the insulin-like growth factors (IGFs) in the hypophysectomized rat: comparison with human growth hormone and the possible role of the specific IGF carrier proteins; Discussion 327 $aProtein phosphorylation and growth controlDiscussion; Receptors for the phorbol ester tumour promoters; Discussion; Ectopic peptides released by a human mela- noma cell line that modulate the transformed phenotype; Discussion; A growth regula- tory factor that can both inhibit and stimulate growth; Discussion; Final general discussion Receptor modulation and signalling systems; Biological functions of growth factors; Medical aspects of growth factors; Index of contributors; Subject index 410 0$aCiba Foundation symposium ;$v116. 606 $aGrowth factors$xPhysiological effect$vCongresses 606 $aCell proliferation$vCongresses 606 $aCells$xGrowth$xRegulation$vCongresses 615 0$aGrowth factors$xPhysiological effect 615 0$aCell proliferation 615 0$aCells$xGrowth$xRegulation 676 $a612/.6 701 $aEvered$b David$0857127 701 $aNugent$b Jonathan$0845868 701 $aWhelan$b Julie$0322651 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144664303321 996 $aGrowth factors in biology and medicine$92117305 997 $aUNINA