LEADER 04425nam 2200685 a 450 001 9910144654903321 005 20230213211704.0 010 $a1-280-78402-4 010 $a9786613694416 010 $a0-470-72076-X 010 $a0-470-71846-3 035 $a(CKB)1000000000688149 035 $a(EBL)703915 035 $a(OCoLC)797918499 035 $a(SSID)ssj0000715494 035 $a(PQKBManifestationID)11400817 035 $a(PQKBTitleCode)TC0000715494 035 $a(PQKBWorkID)10703767 035 $a(PQKB)10330227 035 $a(MiAaPQ)EBC703915 035 $a(Au-PeEL)EBL703915 035 $a(CaPaEBR)ebr10575609 035 $a(CaONFJC)MIL369441 035 $a(EXLCZ)991000000000688149 100 $a19830426d1983 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBrush border membranes$b[electronic resource] 210 $aLondon $cPitman$dc1983 215 $a1 online resource (352 p.) 225 1 $aCiba Foundation symposium ;$vv. 95 300 $aEditors: Ruth Porter (Organizer) and Geralyn M. Collins. 300 $aProceedings of Symposium on: Brush border membranes held at the Ciba Foundation, London, 8-10 June 1982. 311 $a0-470-66413-4 311 $a0-272-79659-X 320 $aIncludes bibliographical references and indexes. 327 $aBrush border membranes; Contents; Chairman's introduction; Introductory remarks on the brush border; Microvillar endopeptidase, an enzyme with special topological features and a wide distribution; Discussion; Aminopeptidases and proteolipids of intestinal brush border; Discussion; Structure of microvillar enzymes in different phases of their life cycles; Discussion; Specific labelling of the hydrophobic domain of rat renal y-glutamyl transferase; Discussion; Biosynthesis and assembly of the largest and major intrinsic polypeptide of the small intestinal brush borders; Discussion 327 $aUse of monoclonal antibodies in the study of intestinal structure and function Discussion; Biosynthesis and transport of plasma membrane glyco- proteins in the rat intestinal epithelial cell: studies with sucrase- isomaltase; Discussion; GENERAL DISCUSSION I Biosynthesis and assembly of brush border proteins: (i) some co-translational models for protein insertion into membranes; molecular sizes of brush border enzymes during assembly; Distribution of enteropeptidase and aminopeptidase to non-brush border sites; General functions of the enterocyte 327 $aMolecular architecture of the microvillus cytoskeleton Discussion; Structure of human placental microvilli; Discussion; Regulation of cytoskeletal structure and contractility in the brush border; Discussion; Characterization of membrane glycoproteins involved in attachment of microfilaments to the microvillar membrane; Discussion; Structural and functional relationship between the membrane and the cytoskeleton in brush border microvilli; Discussion; GENERAL DISCUSSION II A pathological condition due to congenital disorganization of the brush border 327 $aConformational changes in the a-subunit, and cation transport by Na+, K+-ATPase Discussion; Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders; Immunoglobulin G receptors of intestinal brush borders from neonatal rats; Discussion after the preceding two papers; Cotransport systems in the brush border membrane of the human placenta; Discussion; GENERAL DISCUSSION III Cytoskeleton and membrane-cytoskeleton interactions; The importance of structure for understanding the biosynthetic process; Future advances in study of brush border cytoskeleton 327 $aPhoto-affinity labeling to identify components of the neutral amino acid carrier in the intestinal microvillar membrane Chairman's closing remarks; Index to contributors; Subject index 410 0$aCiba Foundation symposium ;$vv. 95. 606 $aCell membranes$vCongresses 606 $aCell physiology$vCongresses 615 0$aCell membranes 615 0$aCell physiology 676 $a611.0181 676 $a611/.0181 701 $aPorter$b Ruth$064811 701 $aCollins$b Geralyn M$0868426 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144654903321 996 $aBrush border membranes$91991734 997 $aUNINA