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010   $a9786612347597
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100   $a19890130d1989      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aGenetic analysis of tumour suppression$b[electronic resource]
210   $aChichester ;$aNew York $cWiley$d1989
215   $a1 online resource (270 p.)
225 1 $aCiba Foundation symposium ;$v142
300   $aProceedings of a symposium held at the Ciba Foundation, London, July 19-21, 1988.
300   $aEditors, Greg Bock, Joan Marsh.
300   $a"A Wiley-Interscience publication."
311   $a0-471-92299-4 
320   $aIncludes bibliographies and indexes.
327   $aGENETIC ANALYSIS OF TUMOUR SUPPRESSION; Contents; Participants; Introduction; Epidemiology of genetically determined cancer; Transgenic mice and host cell mutants resistant to transformation as model systems for identifying multiple components in oncogenesis; Reversion of tumorigenicity in an EBV-converted Burkitt's lymphoma line; Lymphoid neoplasia and the control of haemopoietic differentiation; General discussion I; Loss of genetic information in cancer; General discussion II; The molecular basis of retinoblastomas; General discussion Ill
327   $aProviral position effects: possible probes for genes that suppress transcriptionGeneral discussion IV; Flat revertants of EJ human bladder carcinoma cells show two different mechanisms of reversion; A genetic basis for tumour suppression; Molecular basis for the regulation of cell fate by the lethal (2) giant larvae tumour suppressor gene of Drosophila melanogaster; Suppression of genetic melanoma in the fish Xiphophorus; The biology of tumour suppression; General discussion V; Cell differentiation and tumour suppression; General discussion VI; Final discussion; Index of contributors
327   $aSubject index
330   $aComprises the proceedings of a symposium held at the Ciba Foundation, London, February 1988. Contains the latest research results on the inverse relationship between cell proliferation and differentiation and the nature of the genes involved. Included are the studies of cell fusion experiments, the introduction of single chromosomes into malignant cells, and the transfection of individual genes. Also reports on the role of certain oncogenes in normal development, lineage commitment, and tumorigenesis.
410  0$aCiba Foundation symposium ;$v142.
606   $aTumors$xGenetic aspects$vCongresses
606   $aGene expression$vCongresses
606   $aOncogenes$vCongresses
608   $aElectronic books.
615  0$aTumors$xGenetic aspects
615  0$aGene expression
615  0$aOncogenes
676   $a616.99
676   $a616.994042
701   $aBock$b Gregory$0322650
701   $aMarsh$b Joan$091633
712 02$aCiba Foundation.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910144560503321
996   $aGenetic analysis of tumour suppression$91913945
997   $aUNINA