LEADER 05021nam 2200625 450 001 9910144450503321 005 20170816111606.0 010 $a1-281-94695-8 010 $a9786611946951 010 $a3-527-62262-4 010 $a3-527-62263-2 035 $a(CKB)1000000000556925 035 $a(EBL)482165 035 $a(OCoLC)264621059 035 $a(SSID)ssj0000107000 035 $a(PQKBManifestationID)11133718 035 $a(PQKBTitleCode)TC0000107000 035 $a(PQKBWorkID)10006041 035 $a(PQKB)11313761 035 $a(MiAaPQ)EBC482165 035 $a(PPN)190790784 035 $a(EXLCZ)991000000000556925 100 $a20160819h20082008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAsymmetric phase transfer catalysis /$fedited by Keiji Maruoka 210 1$aWeinheim, [Germany] :$cWiley-VCH Verlag GmbH & Co. KGaA,$d2008. 210 4$dİ2008 215 $a1 online resource (230 p.) 300 $aDescription based upon print version of record. 311 $a3-527-31842-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aAsymmetric Phase Transfer Catalysis; Contents; Preface; List of Contributors; 1 The Basic Principle of Phase-Transfer Catalysis and Some Mechanistic Aspects; 1.1 Introduction; 1.2 Inorganic Base-Promoted Activation of Acidic Organic Compounds; 1.2.1 Generation of Reactive Onium Carbanion Species; 1.2.2 Stability of the Onium Carbanion; 1.2.3 Reactivity of the Onium Carbanion; 1.2.4 Nuclueophilic Substitution Reaction; 1.2.5 Nucleophilic Addition to Electrophilic C=X Double Bonds; 1.3 Phase-Transfer-Catalyzed Addition of Anion Supplied as Metal Salt 327 $a1.4 Use of Crown Ether as Phase-Transfer CatalystReferences; 2 Cinchona-Derived Chiral Phase-Transfer Catalysts for Amino Acid Synthesis; 2.1 Introduction; 2.2 ?-Amino Acid Synthesis; 2.2.1 Monoalkylation of Schiff Bases Derived from Glycine; 2.2.2 Alkylation of Schiff Bases Derived from ?-Alkyl-?-Amino Acids; 2.2.3 Other Alkylations for ?-Amino Acid Synthesis; 2.2.4 Michael Reaction of Glycinate Benzophenone Schiff Bases; 2.2.5 Aldol and Related Reactions; 2.2.6 Aza-Henry Reaction; 2.2.7 Strecker Reaction; 2.2.8 Aziridination; 2.2.9 Radical Reaction; 2.3 ?-Amino Acid Synthesis 327 $a2.3.1 Mannich Reaction2.3.2 Cyclopropanation; 2.4 Conclusions; References; 3 Cinchona-Derived Chiral Phase-Transfer Catalysts for Other Asymmetric Synthesis; 3.1 Introduction; 3.2 Asymmetric Darzens Reaction; 3.3 Asymmetric Conjugated Addition; 3.4 Asymmetric Aldol Reaction; 3.5 Asymmetric Oxygen-Functionalization; 3.6 Asymmetric Alkylation; 3.7 Asymmetric Alkenylation and Alkynylation; 3.8 Asymmetric S(N) Aromatic Reaction; 3.9 Asymmetric Strecker Synthesis; 3.10 Asymmetric Fluorination; References; 4 Cinchona-Derived Chiral Poly(Phase-Transfer Catalysts) for Asymmetric Synthesis 327 $a4.1 Cinchona Alkaloids4.1.1 Cinchona Alkaloids in Asymmetric Phase-Transfer Catalysis; 4.1.2 The Origin of Stereoselectivity of Cinchona-PTCs; 4.2 Development of Dimeric Cinchona-PTCs by the Park-Jew Group; 4.2.1 Dimeric Cinchona-PTCs with Phenyl Linker; 4.2.2 1,3-Dimeric Cinchona-PTCs with Electronically Modified Phenyl Linker; 4.2.3 Polymeric Cinchona-PTCs with Other Linkers; 4.2.4 1,3-Phenyl- and 2,7-Naphthyl-Linked Dimeric Cinchona-PTCs; 4.3 Polymeric PTCs Developed by the Najera Group; 4.4 Polymeric PTCs Developed by the Siva Group; 4.5 Polymeric PTCs Developed by the Wang Group 327 $a4.6 Asymmetric Epoxidation with Polymeric Cinchona-PTCs4.7 Conclusions; References; 5 Binaphthyl- and Biphenyl-Modified Chiral Phase-Transfer Catalysts for Asymmetric Synthesis; 5.1 Introduction; 5.2 Alkylation; 5.2.1 Asymmetric Synthesis of ?-Alkyl ?-Amino Acids and Their Derivatives; 5.2.1.1 Asymmetric Monoalkylation of Glycine Ester Schiff Bases; 5.2.1.2 Asymmetric Monoalkylation of Glycine Amide Schiff Bases; 5.2.1.3 Diastereoselective Alkylation of Glycine Schiff Base with Optically Enriched Alkyl Halides; 5.2.1.4 Recyclable Catalysts and Reagents and Solid-Phase Synthesis 327 $a5.2.1.5 Application of Asymmetric Synthesis of ?-Amino Acids 330 $aEdited by the leading expert on the topic, this is the first book to present the latest developments in this exciting field. Alongside the theoretical aspects, the top contributors provide practical protocols to give readers additional important information otherwise unavailable.A must for every synthetic chemist in academia and industry. 606 $aPhase-transfer catalysis 606 $aAsymmetry (Chemistry) 615 0$aPhase-transfer catalysis. 615 0$aAsymmetry (Chemistry) 676 $a547.215 702 $aMaruoka$b Keiji 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144450503321 996 $aAsymmetric phase transfer catalysis$92288674 997 $aUNINA