LEADER 02536nam 22006014a 450 001 9910144118403321 005 20170810183318.0 010 $a1-281-81450-4 010 $a9786611814502 010 $a0-470-37061-0 010 $a0-470-36916-7 035 $a(CKB)1000000000549398 035 $a(EBL)362144 035 $a(OCoLC)264714700 035 $a(SSID)ssj0000141603 035 $a(PQKBManifestationID)11136183 035 $a(PQKBTitleCode)TC0000141603 035 $a(PQKBWorkID)10058463 035 $a(PQKB)11515335 035 $a(MiAaPQ)EBC362144 035 $a(PPN)198275242 035 $a(EXLCZ)991000000000549398 100 $a20071209d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDrug-DNA interactions$b[electronic resource] $estructures and spectra /$fKazuo Nakamoto, Masamichi Tsuboi, Gary D. Strahan 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2008 215 $a1 online resource (396 p.) 300 $aDescription based upon print version of record. 311 $a0-471-78626-8 320 $aIncludes bibliographical references and index. 327 $aDNA structures and spectra -- Intercalating drugs -- Groove-binding drugs -- Covalent bonding drugs -- Strand-breaking drugs -- Metal-containing drugs. 330 $aLearn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear d 606 $aDNA-drug interactions$xResearch$xMethodology 606 $aDNA$xSpectra 606 $aDrugs$xSpectra 615 0$aDNA-drug interactions$xResearch$xMethodology. 615 0$aDNA$xSpectra. 615 0$aDrugs$xSpectra. 676 $a572.8/6 700 $aNakamoto$b Kazuo$f1922-$023085 701 $aTsuboi$b Masamichi$f1925-$092535 701 $aStrahan$b Gary D$0928917 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144118403321 996 $aDrug-DNA interactions$92087723 997 $aUNINA