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100   $a19920727d1992      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aSecondary metabolites$b[electronic resource] $etheir function and evolution /$f[editors, Derek J. Chadwick and Julie Whelan]
210   $aChichester [England] ;$aNew York $cWiley$d1992
215   $a1 online resource (330 p.)
225 1 $aCiba Foundation symposium ;$v171
300   $a"A Wiley-Interscience publication."
311   $a0-471-93447-X 
320   $aIncludes bibliographical references and indexes.
327   $aSECONDARY METABOLITES: THEIR FUNCTION AND EVOLUTION; Contents; Introduction; Microbial secondary metabolism: a new theoretical frontier for academia, a new opportunity for industry; Evolution of secondary metabolite production: potential roles for antibiotics as prebiotic effectors of catalytic RNA reactions; Why are secondary metabolites synthesized? Sophistication in the inhibition of cell wall biosynthesis by vancomycin group antibiotics; Origins of secondary metabolism; Genes for polyketide secondary metabolic pathways in microorganisms and plants
327   $aGenes for the biosynthesis of B-lactam compounds in microorganismsRegulation of gibberellin formation by the fungus Gibberella fujikuroi; Genetic regulation of secondary metabolic pathways in Streptomyces; Terpenoid cyclases: design and function of electrophilic catalysts; Role of secondary metabolites from microbes; Self-protection mechanisms in antibiotic producers; Useful functions of microbial metabolites; Secondary metabolites from marine organisms; Roles for secondary metabolites in plants; Defensins: endogenous antibiotic peptides from human leukocytes
327   $aFinal discussion: Metabolism and cell individualizationOrigins of secondary metabolism; Index of contributors; Subject index
330   $aA comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary metabolites as natural products having no obvious part to play in the producing organism's life cycle. Covers issues related to genetic and antibiotic applications.
410  0$aCiba Foundation symposium ;$v171.
606   $aMetabolism, Secondary$vCongresses
608   $aElectronic books.
615  0$aMetabolism, Secondary
676   $a574.19
676   $a574.1924
701   $aChadwick$b Derek$091632
701   $aWhelan$b Julie$0322651
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910144012103321
996   $aSecondary metabolites$92041674
997   $aUNINA