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100   $a20080125d2008      uy             0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
182   $cc
183   $acr
200 00$aGalectins$b[electronic resource] /$fedited by Anatole A. Klyosov, Zbigniew J. Witczak, David Platt
210   $aHoboken, N.J. $cJohn Wiley & Sons$dc2008
215   $a1 online resource (302 p.)
300   $aDescription based upon print version of record.
311   $a0-470-37318-0 
320   $aIncludes bibliographical references and index.
327   $aGALECTINS; CONTENTS; Preface; Contributors; 1 Stumbling on Galectins; 2 Galectins and Their Functions in Plain Language; 3 Understanding Galectin Structure-Function Relationships to Design Effective Antagonists; 4 Galectins as Regulators of Tumor Growth and Invasion by Targeting Distinct Cell Surface Glycans and Implications for Drug Design; 5 Nuclear and Cytoplasmic Localization of Galectin-1 and Galectin-3 and Their Roles in Pre-mRNA Splicing; 6 Galectins in Regulation of Inflammation and Immunity
327   $a7 Galectins as Danger Signals in Host-Pathogen and Host-Tumor Interactions: New Members of the Growing Group of ""Alarmins""?8 The Role of Galectins in Organ Fibrosis; 9 Galectin-1, Cancer Cell Migration, Angiogenesis, and Chemoresistance; 10 Galectin-3 in the Progression and Metastasis of Colorectal Neoplasia; 11 Galectins in Malignant Gliomas: Expression, Functions, and Possible Therapeutic Options; 12 Food-Related Carbohydrate Ligands for Galectins; Index
330   $aThe comprehensive guide to the current understanding of galectins and their promising potential in drug design This is the first book focusing on galectins. It was inspired by topics discussed at the symposium ""Galectins: Structures, Functions, and Therapeutic Targets"" that was a part of the 234th American Chemical Society meeting in 2007. To help chemists, biochemists, and others understand the challenges inherent in the study of galectins and build on recent advances in the field, the editors have compiled articles from leading experts on galectins and their biomedical applications.
606   $aLectins
606   $aGalactose
615  0$aLectins.
615  0$aGalactose.
676   $a572/.69
701   $aKlesov$b A. A$g(Anatolii? Alekseevich)$0961316
701   $aWitczak$b Zbigniew J.$f1947-$0285729
701   $aPlatt$b David$f1953-$0961317
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910143829803321
996   $aGalectins$92179512
997   $aUNINA