LEADER 03994nam 22006254a 450 001 9910143581503321 005 20170815111550.0 010 $a1-280-72226-6 010 $a9786610722266 010 $a0-470-05042-X 010 $a0-470-05041-1 035 $a(CKB)1000000000355152 035 $a(EBL)281567 035 $a(OCoLC)163815707 035 $a(SSID)ssj0000227389 035 $a(PQKBManifestationID)11200553 035 $a(PQKBTitleCode)TC0000227389 035 $a(PQKBWorkID)10264794 035 $a(PQKB)11737042 035 $a(MiAaPQ)EBC281567 035 $a(EXLCZ)991000000000355152 100 $a20060314d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPrinciples of mass spectrometry applied to biomolecules$b[electronic resource] /$fedited by Julia Laskin, Chava Lifshitz 210 $aHoboken, N.J. $cWiley-Interscience$dc2006 215 $a1 online resource (707 p.) 225 1 $aWiley-Interscience series in mass spectrometry 300 $aDescription based upon print version of record. 311 $a0-471-72184-0 320 $aIncludes bibliographical references and index. 327 $aPRINCIPLES OF MASS SPECTROMETRY APPLIED TO BIOMOLECULES; CONTENTS; CONTRIBUTORS; PREFACE; PART I STRUCTURES AND DYNAMICS OF GAS-PHASE BIOMOLECULES; 1 Spectroscopy of Neutral Peptides in the Gas Phase: Structure, Reactivity, Microsolvation, Molecular Recognition; 2 Probing the Electronic Structure of Fe-S Clusters: Ubiquitous Electron Transfer Centers in Metalloproteins Using Anion Photoelectron Spectroscopy in the Gas Phase; 3 Ion-Molecule Reactions and H/D Exchange for Structural Characterization of Biomolecules 327 $a4 Understanding Protein Interactions and Their Representation in the Gas Phase of the Mass Spectrometer5 Protein Structure and Folding in the Gas Phase: Ubiquitin and Cytochrome c; 6 Dynamical Simulations of Photoionization of Small Biological Molecules; 7 Intramolecular Vibrational Energy Redistribution and Ergodicity of Biomolecular Dissociation; PART II ACTIVATION, DISSOCIATION, AND REACTIVITY; 8 Peptide Fragmentation Overview; 9 Peptide Radical Cations; 10 Photodissociation of Biomolecule Ions: Progress, Possibilities, and Perspectives Coming from Small-Ion Models 327 $a11 Chemical Dynamics Simulations of Energy Transfer and Unimolecular Decomposition in Collision-Induced Dissociation (CID) and Surface-Induced Dissociation (SID)12 Ion Soft Landing: Instrumentation, Phenomena, and Applications; 13 Electron Capture Dissociation and Other Ion-Electron Fragmentation Reactions; 14 Biomolecule Ion-Ion Reactions; PART III THERMOCHEMISTRY AND ENERGETICS; 15 Thermochemistry Studies of Biomolecules; 16 Energy and Entropy Effects in Gas-Phase Dissociation of Peptides and Proteins; INDEX 330 $aAn extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques. 410 0$aWiley-Interscience series on mass spectrometry. 606 $aMass spectrometry 606 $aBiomolecules$xAnalysis 608 $aElectronic books. 615 0$aMass spectrometry. 615 0$aBiomolecules$xAnalysis. 676 $a543.65 676 $a543/.65 701 $aLaskin$b Julia$f1967-$01000590 701 $aLifshitz$b Chava$01000591 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143581503321 996 $aPrinciples of mass spectrometry applied to biomolecules$92296611 997 $aUNINA