LEADER 04553nam 22006494a 450 001 9910143563503321 005 20170815113522.0 010 $a1-280-55030-9 010 $a9786610550302 010 $a0-471-97316-5 010 $a0-471-97315-7 035 $a(CKB)1000000000355313 035 $a(EBL)270513 035 $a(OCoLC)164438921 035 $a(SSID)ssj0000202277 035 $a(PQKBManifestationID)11171743 035 $a(PQKBTitleCode)TC0000202277 035 $a(PQKBWorkID)10250849 035 $a(PQKB)11188006 035 $a(MiAaPQ)EBC270513 035 $a(EXLCZ)991000000000355313 100 $a20051101d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMicrobial proteomics$b[electronic resource] $efunctional biology of whole organisms /$f[edited by] Ian Humphery-Smith, Michael Hecker 210 $aHoboken, N.J. $cWiley-Liss$dc2006 215 $a1 online resource (540 p.) 225 1 $aMethods of biochemical analysis ;$vv. 49 300 $aDescription based upon print version of record. 311 $a0-471-69975-6 320 $aIncludes bibliographical references and index. 327 $aMICROBIAL PROTEOMICS; CONTENTS; PREFACE; ACKNOWLEDGMENTS; CONTRIBUTORS; PART I GENERAL PROTEOMICS OF MICROORGANISMS/MODEL ORGANISMS; 1. Holistic Biology of Microorganisms: Genomics, Transcriptomics, and Proteomics; 2. Strategies for Measuring Dynamics: The Temporal Component of Proteomics; 3. Quest for Complete Proteome Coverage; 4. Proteome of Mycoplasma pneumoniae; 5. Proteomics of Archaea; PART II PROTEOMICS AND CELL PHYSIOLOGY; 6. Elucidation of Mechanisms of Acid Stress in Listeria monocytogenes by Proteomic Analysis; 7. Oxidation of Bacterial Proteome in Response to Starvation 327 $a8. Tale of Two Metal Reducers: Comparative Proteome Analysis of Geobacter sulferreducens PCA and Shewanella oneidensis MR-19. AMT Tag Approach to Proteomic Characterization of Deinococcus radiodurans and Shewanella oneidensis; PART III PHYSIOLOGICAL PROTEOMICS OF INDUSTRIAL BACTERIA; 10. Proteomics of Corynebacterium glutamicum: Essential Industrial Bacterium; 11. Proteomics of Lactococcus lactis: Phenotypes for a Domestic Bacterium; 12. Proteomic Survey through Secretome of Bacillus subtilis; PART IV PROTEOMICS OF PATHOGENIC MICROORGANISMS 327 $a13. Analyzing Bacterial Pathogenesis at Level of Proteome14. Unraveling Edwardsiella tarda Pathogenesis Using the Proteomics Approach; 15. Structural Proteomics and Computational Analysis of a Deadly Pathogen: Combating Mycobacterium tuberculosis from Multiple Fronts; 16. Proteomic Studies of Plant-Pathogenic Oomycetes and Fungi; 17. Candida albicans Biology and Pathogenicity: Insights from Proteomics; 18. Contributions of Proteomics to Diagnosis, Treatment, and Prevention of Candidiasis; 19. Identification of Protein Candidates for Developing Bacterial Ghost Vaccines against Brucella 327 $a20. Genomics and Proteomics in Reverse VaccinesPART V PROTEOME DATABASES, BIOINFORMATICS, AND BIOCHEMICAL MODELING; 21. Databases and Resources for in silico Proteome Analysis; 22. Interspecies and Intraspecies Comparison of Microbial Proteins: Learning about Gene Ancestry, Protein Function, and Species Life Style; 23. Cellular Kinetic Modeling of the Microbial Metabolism; INDEX 330 $aDiscover important lessons learned about whole organism biology via microbial proteomics This text provides an exhaustive analysis and presentation of current research in the field of microbial proteomics, with an emphasis on new developments and applications and future directions in research. The editors and authors show how and why the relative simplicity of microbes has made them attractive targets for extensive experimental manipulation in a quest for both improved disease prevention and treatment and an improved understanding of whole organism functional biology. 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