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101 0 $aeng
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181   $2rdacontent
182   $2rdamedia
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200 00$aRenin angiotensin system and the heart$b[electronic resource] /$fedited by Walmor C. De Mello
210   $aHoboken, NJ $cJohn Wiley & Sons$dc2004
215   $a1 online resource (258 p.)
300   $aDescription based upon print version of record.
311   $a0-470-86292-0 
320   $aIncludes bibliographical references and index.
327   $aIntracellular signaling and the cardiac renin angiotensin system / George W. Booz and Kenneth M. Baker -- Cardiac physiology and the renin-angiotensin system: lessons from transgenic animal models / Alisdair Ryding and John J. Mullins -- Prorenin uptake in the heart / A.H. Jan Danser -- Role of local renin-angiotensin systems in cardiac damage / Michael Bader -- Cardiac renin: de novo synthesis and uptake / J"rg Peters -- The cardiac renin receptors / Genevie?ve Nguyen, Ce?line Burckle, and Benjamin Tremey -- Angiotensin II AT2 receptors and cardiac function / Jun suzuki ... [et al.] -- The heart, a target for the renin angiotension system: evidence of an intracrine system / Walmor C. De Mello -- ACE2: its role in the counter-regulatory response to heart failure / Lawrence S. Zisman -- Wound healing and the tissue renin-angiotensin-aldosterone system / Yao Sun, and Karl T. Weber -- Trophic effects of aldosterone / Claude Delcayre ... [el al.] -- Intracellular angiotensin and the actions of intracrine hormones / Richard N. Re -- Angiotensin ii and myocardial fibrosis, clinical implications / Begon?a Lo?pez, Arantxa Gonzalez and Javier Di?ez -- Hypertensive heart disease: significance of renin angiotensin system / Jasmina Varagic and Edward D Frohlich.
330   $aRecent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin ang
606   $aRenin-angiotensin system
606   $aHeart$xPhysiology
606   $aHeart$xPathophysiology
615  0$aRenin-angiotensin system.
615  0$aHeart$xPhysiology.
615  0$aHeart$xPathophysiology.
676   $a612.17
676   $a616.12061
701   $aDe Mello$b Walmor C$0965289
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910143550703321
996   $aRenin angiotensin system and the heart$92190177
997   $aUNINA