LEADER 05242nam 2200649Ia 450 001 9910143301903321 005 20180727163339.0 010 $a1-281-30841-2 010 $a9786611308414 010 $a0-470-76178-4 010 $a0-470-69186-7 010 $a1-4051-8151-6 035 $a(CKB)1000000000341901 035 $a(EBL)306568 035 $a(OCoLC)437186579 035 $a(SSID)ssj0000257588 035 $a(PQKBManifestationID)11194616 035 $a(PQKBTitleCode)TC0000257588 035 $a(PQKBWorkID)10246679 035 $a(PQKB)11553507 035 $a(MiAaPQ)EBC306568 035 $a(EXLCZ)991000000000341901 100 $a20060426d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aTextbook of hepatology$b[electronic resource] $efrom basic science to clinical practice 205 $a3rd ed. 210 $aMalden, MA $cBlackwell$dc2007 215 $a1 online resource (2358 p.) 300 $aRev. ed. of: Oxford textbook of clinical hepatology. 2nd ed. 1999. 311 $a1-4051-2741-4 320 $aIncludes bibliographical references and indexes. 327 $aTEXTBOOK OF Hepatology : From Basic Science to Clinical Practice; Contents; Contributors; Foreword; Preface to the third edition; Preface to the first edition; Volume One; Section 1 Architecture of the liver; 1.1 Macroscopic anatomy of the liver; 1.2 Liver and biliary tract histology; 1.3 Ultrastructure of the hepatocyte; 1.4 Liver sinusoidal endothelial cells; 1.5 Kupffer cells; 1.6 The hepatic stellate cell; 1.7 Biliary epithelial cells; 1.8 Hepatic stem cells; 1.9 Embryology of the liver and intrahepatic biliary tract; Section 2 Functions of the liver; 2.1 Hepatic circulation 327 $a2.1.1 Regulation of hepatic blood flow2.1.2 Hepatic microcirculation; 2.1.3 Hepatic lymph and lymphatics; 2.2 Functions of the liver; 2.2.1 Functional organization of the liver; 2.2.2 Cell biology of the hepatocyte; 2.2.3 Molecular biology of the liver cell; 2.2.4 Hepatic transport processes; 2.2.5 Modulation of liver function by hepatic nerves; 2.2.6 In vitro techniques: isolated organ perfusion, slices, cells and subcellular elements; 2.3 Metabolism; 2.3.1 Carbohydrates and the liver; 2.3.2 Lipoprotein metabolism; 2.3.3 Protein and amino acid metabolism 327 $a2.3.4 Mitochondria and energy formation2.3.5 Bilirubin metabolism; 2.3.6 Metabolism of bile acids; 2.3.7 Ammonia, urea production and pH regulation; 2.3.8 Protein synthesis and degradation in the liver; 2.3.9 Glutathione; 2.3.10 Haem biosynthesis and excretion of porphyrins; 2.3.11 Vitamins and the liver (A and D); 2.3.12 Normal iron metabolism; 2.3.13 Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes; 2.3.14 Trace elements and the liver; 2.3.15 Hepatic metabolism of drugs; 2.4 Synthetic function; 2.4.1 Albumin and other carrier proteins 327 $a2.4.2 The liver and coagulation2.4.3 Function and metabolism of collagen and other extracellular matrix proteins; 2.5 Regulation of the liver cell mass; 2.5.1 Control of liver cell proliferation; 2.5.2 Regeneration of chronically injured liver; 2.6 Excretion; 2.6.1 Physiology of bile formation; 2.6.2 Motility of the biliary tree; 2.7 Immunology of the liver; 2.7.1 Cytokines in liver physiology and pathology; 2.7.2 Intrahepatic lymphocytes; 2.7.3 Antibody production and transport in the liver; Section 3 Basic concepts in pathobiology; 3.1 Hepatocyte apoptosis and necrosis 327 $a3.2 Ischaemia...reperfusion injury to the liver3.3 Genetics and liver diseases; 3.3.1 Genetic polymorphisms in liver disease; 3.3.2 Immunogenetics of liver disease; 3.3.3 Genetic determinants of complex liver diseases: mouse models and quantitative trait locus analysis; 3.4 Cellular cholestasis; 3.5 Oncogenes and tumour suppressor genes; 3.6 Genomics, gene arrays and proteomics in the study of liver disease; Section 4 Pathology; 4.1 Histological features; 4.2 Classifications, scoring systems and morphometry in liver pathology; Section 5 Investigation of hepatobiliary disease 327 $a5.1 Signs and symptoms of liver disease 330 $aTHE encyclopedic guide to hepatology - for consultation by clinicians and basic scientists Previously the Oxford Textbook of Clinical Hepatology, this two-volume textbook is now with Blackwell Publishing. It covers basic, clinical and translational science (converting basic science discoveries into the practical applications to benefit people). Edited by ten leading experts in the liver and biliary tract and their diseases, along with outstanding contributions from over 200 international clinicians, this text has global references, evidence and extensive subject matter 606 $aLiver$xDiseases 606 $aLiver$xTumors 608 $aElectronic books. 615 0$aLiver$xDiseases. 615 0$aLiver$xTumors. 676 $a616.3/62 676 $a616.362 701 $aRode?s$b Joan$0880074 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143301903321 996 $aTextbook of hepatology$91965141 997 $aUNINA