LEADER 05737nam 22008294a 450 001 9910143280703321 005 20251116151027.0 010 $a9786610198252 010 $a9780470777480 010 $a0470777486 010 $a9781280198250 010 $a1280198257 010 $a9780470774595 010 $a0470774592 010 $a9781405128315 010 $a1405128313 035 $a(CKB)1000000000342204 035 $a(EBL)214213 035 $a(OCoLC)437065744 035 $a(SSID)ssj0000166669 035 $a(PQKBManifestationID)11156894 035 $a(PQKBTitleCode)TC0000166669 035 $a(PQKBWorkID)10162078 035 $a(PQKB)11399271 035 $a(MiAaPQ)EBC214213 035 $a(Au-PeEL)EBL214213 035 $a(CaPaEBR)ebr10236687 035 $a(CaONFJC)MIL19825 035 $a(OCoLC)50959010 035 $a(FINmELB)ELB179196 035 $a(Perlego)2768945 035 $a(iGPub)WILEYB0005645 035 $a(EXLCZ)991000000000342204 100 $a20021028d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aGut flora, nutrition, immunity and health /$fedited by Roy Fuller & Gabriela Perdigon 205 $a1st ed. 210 $aOxford ;$aMalden, MA $cBlackwell Pub.$d2003 215 $a1 online resource (290 p.) 300 $aDescription based upon print version of record. 311 08$a9781405100007 311 08$a1405100001 320 $aIncludes bibliographical references and index. 327 $aContents; Preface; Acknowledgements; 1 The Intestinal Microflora; From Petri dish to polyacrylamide gel; Catalogues show diversity; A phoenix arises; Is it all the same in the end?; The formative years; Rules and regulations, but mind your language; 2 Food and the Large Intestine; The large intestine; Interactions of the microflora with the host; Effect of diet on the colonic microflora; Diet and bacterial species composition in the large intestine; Diet and bacterial metabolism; Intestinal bacteria and vitamins; Bacterial growth substrates in the large intestine 327 $aBreakdown of complex carbohydrates by intestinal bacteriaProtein breakdown by gut microorganisms; Toxological implications of amino acid fermentation; Effects of carbohydrate on amino acid fermentation; Short-chain fatty acids; Effect of diet on SCFA production; In vitro studies on SCFA production; SCFA and cell metabolism; SCFA and colon cancer; Lactate formation by gut microorganisms; 3 The Health Benefits of Probiotics and Prebiotics; Summary; Introduction; Probiotics; Composition of probiotic preparations; Tracking probiotics through the gut; Prebiotics; Oligosaccharides as prebiotics 327 $aLactuloseInulin and fructooligosaccharides; Galactooligosaccharides; Soybean oligosaccharides; Lactosucrose; Isomaltooligosaccharides; Glucooligosaccharides; Xylooligosaccharides; Current status; Persistence of the prebiotic effect to distal regions of the colon; Anti-adhesive activities against pathogens and toxins; Targeted prebiotics; Attenuative properties; Defined health outcomes of probiotics and prebiotics; Improved tolerance to lactose; Protection from gastroenteritis; Coronary heart disease; Colon cancer; Vitamin synthesis; Irritable bowel syndrome 327 $aImproved digestion and gut functionImmunomodulation; Mineral bioavailability; Conclusions; 4 Intestinal Microflora and Metabolic Activity; Dietary carbohydrates; Bacterial fermentation; SCFA production; SCFA and electrolytes absorption; Colonic metabolism; Physiological consequences of SCFA absorption; Probiotics and the intestinal metabolism of carbohydrates; 5 The Role of the Immune System; Overview of the immune system; Introduction; Innate immune response; Early induced immune response; Adaptative immune response; B lymphocytes and the immunoglobulins 327 $aT lymphocytes and the T cell receptor complexAPCs and the MHC molecules; Education of lymphocytes in the primary lymphoid organs; Education of T lymphocytes in the thymus; Education of B lymphocytes in the bone marrow; The immune system functioning; Peripheral lympoid tissues, a place where lymphocytes meet the antigen; Lymphocyte traffic; Activation of T cells; Cell-mediated immune response: generation of armed effector T cells; Generation of Thl and Th2 cells; Cytotoxic T cells; Humoral immune response; Activation of B cells in the secondary lymphoid organs; Kinetics of the immune response 327 $aEndogenous regulation of the immune response 330 $aSome foods, as well as contributing essential nutrients to the body, also contain additional components that improve disease resistance and general health status over and above that induced by ingestion of conventional foods. The so-called functional foods, and prebiotics and probiotics exemplify the relationship that exists between nutrition, the gut (the largest element of the body's immune system) and its flora, immunology and health. This important book contains chapters covering the basic principles of nutrition, gut microecology and immunology, as well as chapters which disc 606 $aIntestines$xMicrobiology 606 $aNutrition 606 $aFunctional foods 606 $aDigestion 615 0$aIntestines$xMicrobiology. 615 0$aNutrition. 615 0$aFunctional foods. 615 0$aDigestion. 676 $a612.3 701 $aFuller$b R$0857811 701 $aPerdigo?n$b G$g(Gabriela)$0857812 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143280703321 996 $aGut flora, nutrition, immunity and health$91915384 997 $aUNINA