LEADER 03780nam 2200649Ia 450 001 9910143271203321 005 20251017110119.0 010 $a1-000-61155-8 010 $a0-429-11457-5 010 $a1-281-08125-6 010 $a9786611081256 010 $a1-4200-0552-9 024 7 $a10.1201/9781420005523 035 $a(CKB)1000000000345018 035 $a(EBL)291218 035 $a(OCoLC)137292445 035 $a(SSID)ssj0000114253 035 $a(PQKBManifestationID)11143085 035 $a(PQKBTitleCode)TC0000114253 035 $a(PQKBWorkID)10101479 035 $a(PQKB)10544825 035 $a(MiAaPQ)EBC291218 035 $a(DNLM)1291259 035 $a(EXLCZ)991000000000345018 100 $a20061108d2007 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBrain aging $emodels, methods, and mechanisms /$fedited by David R. Riddle 210 $aBoca Raton, Fla. $cCRC ;$aLondon $cTaylor & Francis [distributor]$d2007 215 $a1 online resource (414 p.) 225 1 $aFrontiers in neuroscience 300 $aDescription based upon print version of record. 311 08$a0-367-45310-X 311 08$a0-8493-3818-2 320 $aIncludes bibliographical references and index. 327 $aFront cover; Table of Contents; Series Preface; Preface; About the Editor; Contributors; Section I: Assessing Cognitive Aging; Chapter 1. Changes in Cognitive Function in Human Aging; Chapter 2. Successful vs. Unsuccessful Aging in the Rhesus Monkey; Chapter 3. Neuropsychology of Cognitive Aging in Rodents; Section II: Quantifying Aging-Related Changes in the Brain; Chapter 4. Design-Based Stereology in Brain Aging Research; Chapter 5. The Effects of Normal Aging on Nerve Fibers and Neuroglia in the Central Nervous System; Chapter 6. Neurogenesis in the Adult and Aging Brain 327 $aChapter 7. Expression Profile Analysis of Brain AgingSection III: Assessing Functional Changes in the Aging Nervous System; Chapter 8. Subtle Alterations in Glutamatergic Synapses Underlie the Aging- Related Decline in Hippocampal Function; Chapter 9. Assessment of Second Messenger Function in the Hippocampus of Aged Rats with Cognitive Impairment; Chapter 10. Neurophysiology of Old Neurons and Synapses; Chapter 11. Imaging Cognition in the Aging Human Brain; Section IV: Mechanisms Contributing to Brain Aging; Chapter 12. Regulation of Cerebrovascular Aging 327 $aChapter 13. Stress and Glucocorticoid Contributions to Normal and Pathological AgingChapter 14. Altered Calcium Homeostasis in Old Neurons; Chapter 15. Oxidative Stress and the Aging Brain: From Theory to Prevention; Index; Back cover 330 $aRecognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur, new possibilities emerge for limiting the effects of aging on neural function. A single source reference is necessary to keep abreast of the recent advances and future directions of gerontology research. Brain Aging: Models, Methods, and 410 0$aFrontiers in neuroscience. 606 $aBrain$xAging 606 $aBrain$xPathophysiopathology 615 0$aBrain$xAging. 615 0$aBrain$xPathophysiopathology. 676 $a612.67 686 $a44.90$2bcl 701 $aRiddle$b David R$01213684 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143271203321 996 $aBrain aging$92802926 997 $aUNINA