LEADER 05435nam 2200685Ia 450 001 9910143263903321 005 20221121150521.0 010 $a1-280-21343-4 010 $a9786610213436 010 $a0-470-79017-2 010 $a0-470-77457-6 010 $a1-4051-4810-1 035 $a(CKB)1000000000351677 035 $a(EBL)238471 035 $a(OCoLC)475948896 035 $a(SSID)ssj0000268184 035 $a(PQKBManifestationID)11218103 035 $a(PQKBTitleCode)TC0000268184 035 $a(PQKBWorkID)10235407 035 $a(PQKB)11238591 035 $a(MiAaPQ)EBC238471 035 $a(EXLCZ)991000000000351677 100 $a20020805d2004 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aVitamins$b[electronic resource] $etheir role in the human body /$fG.F.M. Ball 210 $aOxford $cBlackwell Science$d2004 215 $a1 online resource (450 p.) 300 $aDescription based upon print version of record. 311 $a0-632-06478-1 320 $aIncludes bibliographical references and index. 327 $aContents; 8.7 Immunoregulatory properties; 8.11 Toxicity; Further reading; Foreword; Preface; 1 Historical Events Leading to the Establishment of Vitamins; 1.1 Introduction; 1.2 Early studies of nutritionally related diseases; 1.3 Experiments on formulated diets; 1.4 Naming of the vitamins; Further reading; References; 2 Nutritional Aspects of Vitamins; 2.1 Definition and classification of vitamins; 2.2 Nutritional vitamin deficiency; 2.3 Stability and bioavailability of vitamins; 2.4 Vitamin requirements; Further reading; References; 3 Background Physiology and Functional Anatomy 327 $a3.1 Movement of solutes across cell membranes and epithelia3.2 The blood-brain, blood-cerebrospinal fluid and placental barriers; 3.3 Functional anatomy of the small and large intestine, liver and kidney; 3.4 Digestion and absorption; 3.5 Glucose transport; 3.6 Digestion, absorption and transport of dietary fat; 3.7 Neural and endocrine communication systems; 3.8 Structure of bone and its growth and development; 3.9 Cell proliferation; Further reading; References; 4 Background Biochemistry; 4.1 Major degradation pathways in which B-group vitamins are involved as coenzymes 327 $a4.2 Amino acid utilization4.3 Defences against free radicals and other reactive species; 4.4 Haemostasis; 4.5 Atherosclerosis; Further reading; References; 5 Background Immunology; 5.1 General features of the immune system; 5.2 Innate immunity; 5.3 Inflammation; 5.4 Acquired immunity; 5.5 Cytokines; 5.6 Hypersensitivity; 5.7 Immune suppression; 5.8 Neuroendocrine modulation of immune responses; Further reading; References; 6 The Genetic Control of Protein Synthesis and its Regulation by Nuclear Hormone Receptors; 6.1 Functional structure of DNA; 6.2 Role of RNA in protein synthesis 327 $a6.3 Gene expression6.4 Mutation and polymorphism; 6.5 Basal transcription; 6.6 Regulated transcription; 6.7 Jun, Fos and the AP-1 complex; 6.8 Nuclear hormone receptors as regulators of protein synthesis; Further reading; References; 7 Vitamin A: Retinoids and Carotenoids; 7.1 Historical overview; 7.2 Chemistry and biological functions; 7.3 Dietary sources; 7.4 Absorption, transport and metabolism; 7.5 Nutritional factors that influence vitamin A status; 7.6 The role of vitamin A in vision; 7.7 Retinoids as regulators of gene expression; 7.8 Effects of vitamin A on the immune system 327 $a7.9 Role of vitamin A in bone metabolism and embryonic development7.10 Vitamin A and cancer; 7.11 Vitamin A deficiency and toxicity; Further reading; References; 8 Vitamin D; 8.1 Historical overview; 8.2 Chemistry and biological functions; 8.3 Dietary sources; 8.4 Cutaneous synthesis, intestinal absorption, transport and metabolism; 8.5 Molecular action of the vitamin D hormones; 8.6 Calcium and phosphate homeostasis; 8.8 Effects of vitamin D on insulin secretion; 8.9 Vitamin D-related diseases; 8.10 Therapeutic applications of vitamin D analogues; 8.12 Dietary requirement; Further reading 327 $aReferences 330 $aThis single-source reference draws together the current knowledge of the vitamins' biological properties in the context of human nutrition. Vitamins are co-enzymes, antioxidants or precursors of hormones and are therefore involved in a great many biochemical and physiological processes. They play a vital role in the maintenance of health, and there is evidence that dietary sources of vitamins have beneficial effects in the prevention of heart-related diseases, bone diseases and possibly cancer.Following introductory chapters on historical and nutritional aspects of vitamins, th 606 $aVitamins$xPhysiological effect 606 $aVitamins in human nutrition 606 $aVitamines en la nutrició humana$2thub 608 $aElectronic books. 608 $aLlibres electrònics$2thub 615 0$aVitamins$xPhysiological effect. 615 0$aVitamins in human nutrition. 615 7$aVitamines en la nutrició humana 676 $a612.399 676 $a613.2/86 676 $a613.286 700 $aBall$b G. F. M$0969189 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143263903321 996 $aVitamins$92202104 997 $aUNINA