LEADER 03956nam 2200673Ia 450 001 9910143231003321 005 20170810191552.0 010 $a1-280-27080-2 010 $a9780470857900 010 $a9786610270804 010 $a0-470-66805-9 010 $a0-470-85790-0 010 $a0-470-85789-7 035 $a(CKB)111087027094326 035 $a(EBL)152692 035 $a(OCoLC)54049454 035 $a(SSID)ssj0000177810 035 $a(PQKBManifestationID)11182258 035 $a(PQKBTitleCode)TC0000177810 035 $a(PQKBWorkID)10218802 035 $a(PQKB)10258081 035 $a(MiAaPQ)EBC152692 035 $a(EXLCZ)99111087027094326 100 $a20020919d2002 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$a'In silico' simulation of biological processes$b[electronic resource] /$f[editors, Gregory Bock and Jamie A. Goode] 210 $aChichester, West Sussex, UK ;$aHoboken, NJ $cJohn Wiley$d2002 215 $a1 online resource (272 p.) 225 1 $aNovartis Foundation symposium ;$v247 300 $a"Symposium on 'In silico' simulation of biological processes, held at the Novartis Foundation, London, 27-29 November 2001"--Contents p. 311 $a0-470-84480-9 320 $aIncludes bibliographical references and indexes. 327 $a'IN SILICO' SIMULATION OF BIOLOGICAL PROCESSES; Contents; Participants; Chair's introduction; Integrative biological modelling in silico; Discussion; Advances in computing, and their impact on scientific computing; Discussion; From physics to phenomenology. Levels of description and levels of selection; Making sense of complex phenomena in biology; Discussion; On ontologies for biologists: the Gene Ontology-untangling the web; Discussion; General discussion I; Model validation; The KEGG database; Discussion; Bioinformatics of cellular signalling; Discussion; General discussion II 327 $aStandards of communicationSemantics and intercommunicability; Imaging-based integrative models of the heart: closing the loop between experiment and simulation; Discussion; General discussion III; Modelling Ca(2+) signalling; The Virtual Cell project; Discussion; Modelling the bacterial chemotaxis receptor complex; The heart cell in silico: successes, failures and prospects; Discussion; Discussion; General discussion IV; The IUPS Physiome Project; Discussion; Using in silico biology to facilitate drug development; Discussion; Final discussion; Is there a theoretical biology? 327 $aIndex of contributorsSubject index 330 $aOver recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies must now be used to perform this integration. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes. The initial chapters deal with fund 410 0$aNovartis Foundation symposium ;$v247. 606 $aBiology$xComputer simulation$vCongresses 606 $aBioinformatics$vCongresses 608 $aElectronic books. 615 0$aBiology$xComputer simulation 615 0$aBioinformatics 676 $a570/.1/13 676 $a660.6 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 712 02$aNovartis Foundation. 712 12$aSymposium on 'In Silico' Simulation of Biological Processes$f(2001 :$eLondon, England) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143231003321 996 $aIn silico' simulation of biological processes$92296636 997 $aUNINA LEADER 02119oam 2200481 450 001 9910707359903321 005 20160718154325.0 035 $a(CKB)5470000002463918 035 $a(OCoLC)891382732 035 $a(EXLCZ)995470000002463918 100 $a20140926d1971 ua 0 101 0 $aeng 135 $aurbn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCretaceous and lower Tertiary stratigraphy of the Gurabo and El Yunque quadrangles, Puerto Rico $ea description of the largely marine-deposited volcaniclastic rocks and subordinate lava flows and pelagic mudstones that underlie this part of eastern Puerto Rico /$fby Victor M. Seiders 210 1$a[Washington, D.C.] :$cUnited States Department of the Interior, Geological Survey,$d1971. 210 2$aWashington :$cUnited States Government Printing Office. 215 $a1 online resource (iv, 58 pages, 1 page of plates) $cmaps 225 1 $aGeological Survey bulletin ;$v1294-F 225 1 $aContributions to stratigraphy 300 $aTitle from title screen (viewed September 15, 2014). 300 $a"Prepared in cooperation with the Commonwealth of Puerto Rico Economic Development Administration, Industrial Research Department." 320 $aIncludes bibliographical references (pages 52-53) and index. 517 $aCretaceous and lower Tertiary stratigraphy of the Gurabo and El Yunque quadrangles, Puerto Rico 606 $aGeology$zPuerto Rico 606 $aGeology, Stratigraphic$yCretaceous 606 $aGeology, Stratigraphic$yTertiary 615 0$aGeology 615 0$aGeology, Stratigraphic 615 0$aGeology, Stratigraphic 700 $aSeiders$b Victor M.$01389466 712 02$aGeological Survey (U.S.), 712 02$aPuerto Rico.$bDepartment of Industrial Research, 801 0$bCOP 801 1$bCOP 801 2$bOCLCO 801 2$bGPO 906 $aBOOK 912 $a9910707359903321 996 $aCretaceous and lower Tertiary stratigraphy of the Gurabo and El Yunque quadrangles, Puerto Rico$93538515 997 $aUNINA