LEADER 03709nam 22006494a 450 001 9910143227003321 005 20170810191620.0 010 $a1-280-27237-6 010 $a9786610272372 010 $a0-470-66751-6 010 $a0-470-86937-2 010 $a0-470-86938-0 035 $a(CKB)111087027098542 035 $a(EBL)164856 035 $a(OCoLC)475873713 035 $a(SSID)ssj0000107801 035 $a(PQKBManifestationID)11108952 035 $a(PQKBTitleCode)TC0000107801 035 $a(PQKBWorkID)10016087 035 $a(PQKB)10452769 035 $a(MiAaPQ)EBC164856 035 $a(EXLCZ)99111087027098542 100 $a20030411d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAutism$b[electronic resource] $eneural basis and treatment possibilities /$f[editors, Gregory Bock and Jamie Goode] 210 $aHoboken, NJ $cWiley$d2003 215 $a1 online resource (322 p.) 225 1 $aNovartis Foundation symposium ;$v251 300 $aSymposium on autism: neural basis and treatment possibilities, held at the Novartis Foundation, London, 18-20 June 2002. 311 $a0-470-85099-X 320 $aIncludes bibliographical references and indexes. 327 $aAUTISM: NEURAL BASIS AND TREATMENT POSSIBILITIES; Contents; Participants; Introduction: autism - the challenges ahead; Epidemiology and early identification of autism: research challenges and opportunities; Discussion; Implications of the broader phenotype for concepts of autism; Discussion; Strategies for autism candidate gene analysis; Discussion; How might genetic mechanisms operate in autism?; Discussion; X-linked genes and the neural basis of social cognition; Discussion; General discussion I; The neuropathology of the autism spectrum disorders: what have we learned?; Discussion 327 $aMicrobiology and immunology of autism spectrum disordersDiscussion; What do imaging studies tell us about the neural basis of autism?; Discussion; The amygdala, autism and anxiety; Discussion; Cognition in autism: one deficit or many?; Discussion; Autism and specific language impairment: categorical distinction or continuum?; Discussion; Why have drug treatments been so disappointing?; Discussion; Can early interventions alter the course of autism?; Discussion; Early intervention and brain plasticity in autism; Discussion; Final discussion; Summing-up; Index of contributors; Subject index 330 $aThis book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a different field, providing a balanced view of the whole spectrum of study of this disorder. It covers four main areas: * Twin and family studies indicate that the heritability of the underlying liability to autism exceeds 90% and point to a multifactorial causation, involving a relatively small number of susceptibility genes. The book discusses this issue in detail, along with the problem of why s 410 0$aNovartis Foundation symposium ;$v251. 606 $aAutism$vCongresses 606 $aAutism in children$vCongresses 606 $aNeurophysiology$vCongresses 608 $aElectronic books. 615 0$aAutism 615 0$aAutism in children 615 0$aNeurophysiology 676 $a616.85882 676 $a618.92/8982 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143227003321 996 $aAutism$92068282 997 $aUNINA