LEADER 05352nam 2200673Ia 450 001 9910143176303321 005 20170815114003.0 010 $a1-280-36663-X 010 $a9786610366637 010 $a0-470-35122-5 010 $a1-61344-244-0 010 $a0-471-46109-1 010 $a0-471-22384-0 035 $a(CKB)111087027125446 035 $a(EBL)159851 035 $a(OCoLC)475872822 035 $a(SSID)ssj0000182456 035 $a(PQKBManifestationID)11182586 035 $a(PQKBTitleCode)TC0000182456 035 $a(PQKBWorkID)10167037 035 $a(PQKB)11139395 035 $a(MiAaPQ)EBC159851 035 $a(EXLCZ)99111087027125446 100 $a20011107d2002 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 13$aAn introduction to computational biochemistry$b[electronic resource] /$fC. Stan Tsai 210 $aNew York $cJ. Wiley$dc2002 215 $a1 online resource (380 p.) 300 $aDescription based upon print version of record. 311 $a0-471-40120-X 320 $aIncludes bibliographical references and index. 327 $aAN INTRODUCTION TO COMPUTATIONAL BIOCHEMISTRY; CONTENTS; Preface; 1 INTRODUCTION; 1.1. Biochemistry: Studies of Life at the Molecular Level; 1.2. Computer Science and Computational Sciences; 1.3. Computational Biochemistry: Application of Computer Technology to Biochemistry; References; 2 BIOCHEMICAL DATA: ANALYSIS AND MANAGEMENT; 2.1. Statistical Analysis of Biochemical Data; 2.2. Biochemical Data Analysis with Spreadsheet Application; 2.3. Biochemical Data Management with Database Program; 2.4. Workshops; References; 3 BIOCHEMICAL EXPLORATION: INTERNET RESOURCES 327 $a3.1. Introduction to Internet3.2. Internet Resources of Biochemical Interest; 3.3. Database Retrieval; 3.4. Workshops; References; 4 MOLECULAR GRAPHICS: VISUALIZATION OF BIOMOLECULES; 4.1. Introduction to Computer Graphics; 4.2. Representation of Molecular Structures; 4.3. Drawing and Display of Molecular Structures; 4.4. Workshops; References; 5 BIOCHEMICAL COMPOUNDS: STRUCTURE AND ANALYSIS; 5.1. Survey of Biomolecules; 5.2. Characterization of Biomolecular Structures; 5.3. Fitting and Search of Biomolecular Data and Information; 5.4. Workshops; References 327 $a6 DYNAMIC BIOCHEMISTRY: BIOMOLECULAR INTERACTIONS6.1. Biomacromolecule-Ligand Interactions; 6.2. Receptor Biochemistry and Signal Transduction; 6.3. Fitting of Binding Data and Search for Receptor Databases; 6.4. Workshops; References; 7 DYNAMIC BIOCHEMISTRY: ENZYME KINETICS; 7.1. Characterization of Enzymes; 7.2. Kinetics of Enzymatic Reactions; 7.3. Search and Analysis of Enzyme Data; 7.4. Workshops; References; 8 DYNAMIC BIOCHEMISTRY: METABOLIC SIMULATION; 8.1. Introduction to Metabolism; 8.2. Metabolic Control Analysis; 8.3. Metabolic Databases and Simulation; 8.4. Workshops; References 327 $a9 GENOMICS: NUCLEOTIDE SEQUENCES AND RECOMBINANT DNA9.1. Genome, DNA Sequence, and Transmission of Genetic Information; 9.2. Recombinant DNA Technology; 9.3. Nucleotide Sequence Analysis; 9.4. Workshops; References; 10 GENOMICS: GENE IDENTIFICATION; 10.1. Genome Information and Features; 10.2. Approaches to Gene Identification; 10.3. Gene Identification with Internet Resources; 10.4. Workshops; References; 11 PROTEOMICS: PROTEIN SEQUENCE ANALYSIS; 11.1. Protein Sequence: Information and Features; 11.2. Database Search and Sequence Alignment 327 $a11.3. Proteomic Analysis Using Internet Resources: Sequence and Alignment11.4. Workshops; References; 12 PROTEOMICS: PREDICTION OF PROTEIN STRUCTURES; 12.1. Prediction of Protein Secondary Structures from Sequences; 12.2. Protein Folding Problems and Functional Sites; 12.3. Proteomic Analysis Using Internet Resources: Structure and Function; 12.4. Workshops; References; 13 PHYLOGENETIC ANALYSIS; 13.1. Elements of Phylogeny; 13.2. Methods of Phylogenetic Analysis; 13.3. Application of Sequence Analyses in Phylogenetic Inference; 13.4. Workshops; References 327 $a14 MOLECULAR MODELING: MOLECULAR MECHANICS 330 $aThis comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in 606 $aBiochemistry$xData processing 606 $aBiochemistry$xComputer simulation 606 $aBiochemistry$xMathematics 608 $aElectronic books. 615 0$aBiochemistry$xData processing. 615 0$aBiochemistry$xComputer simulation. 615 0$aBiochemistry$xMathematics. 676 $a572.0285 676 $a572/.0285 700 $aTsai$b C. Stan$0869811 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143176303321 996 $aAn introduction to computational biochemistry$92131936 997 $aUNINA