LEADER 03824nam 2200601Ia 450 001 9910143141903321 005 20170815170022.0 010 $a1-282-11855-2 010 $a9786612118555 010 $a3-527-62752-9 010 $a3-527-62753-7 035 $a(CKB)1000000000766420 035 $a(EBL)481241 035 $a(OCoLC)441874995 035 $a(SSID)ssj0000170457 035 $a(PQKBManifestationID)11164181 035 $a(PQKBTitleCode)TC0000170457 035 $a(PQKBWorkID)10235013 035 $a(PQKB)10402722 035 $a(MiAaPQ)EBC481241 035 $a(PPN)194593681 035 $a(EXLCZ)991000000000766420 100 $a20080429d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHereditary tumors$b[electronic resource] $efrom genes to clinical consequences /$fedited by Heike Allgayer, Helga Rehder and Simone Fulda 210 $aWeinheim $cWiley-VCH$dc2009 215 $a1 online resource (562 p.) 300 $aDescription based upon print version of record. 311 $a3-527-32028-8 320 $aIncludes bibliographical references and index. 327 $aHereditary Tumors; Foreword; Preface; Contents; List of Contributors; Part I Hereditary Tumors - General Aspects; 1 General Insights Into Tumor Invasion, Progression, and Metastasis; 2 The Genetic Background of Hereditary Tumor Diseases; Part II Syndromal Types of Hereditary Tumors; 3 Family Cancer Syndromes; 4 Genetic Dysmorphic Syndromes Leading to Tumorigenesis; Part III Site-Specific Aspects of Hereditary Tumors; 5 Hereditary Brain Tumors; 6 Neurofibromatosis; 7 Retinoblastoma: The Prototypic Hereditary Tumor; 8 Hereditary Cancer in the Head and Neck 327 $a9 Hereditary Medullary and Familial Non-Medullary Thyroid Carcinoma10 Lung Tumors; 11 Hereditary Breast Cancer; 12 Hereditary Ovarian and Endometrial Cancer; 13 Prostate Cancer; 14 Wilms and Rhabdoid Tumors of the Kidney; 15 Hereditary Renal Tumors of the Adult; 16 Gastrointestinal Polyposis Syndromes; 17 Lynch Syndrome (HNPCC); 18 Gastrointestinal Stromal Tumors (GISTs); 19 Hereditary Gastric Cancer; 20 Pancreatic Cancer; 21 Liver Tumors; 22 DNA-Repair Deficiency and Cancer: Lessons from Lymphoma; 23 Familial Leukemias; 24 Malignant Melanoma 327 $a25 Xeroderma Pigmentosum, Cockayne Syndrome, Trichothiodystrophy - Defects in DNA Repair and Carcinogenesis26 Hereditary Tumors in Children; 27 Sarcomas and Bone Tumors in Adulthood; Part IV Genetic Counseling, Psycho-Oncology, and General Perspectives for Therapeutic Strategies; 28 Genetic Counseling for Hereditary Tumors; 29 Psycho-Oncologic Aspects of Hereditary Tumors and Predictive Testing; 30 Molecular Targeted Therapy; Index 330 $aSummarizing molecular aspects, diagnostic as well as therapeutic issues, this book is the very first and most comprehensive on hereditary aspects of tumor diseases. All the contributors have been made fellows of the Ingrid zu Solms Foundation due to their outstanding achievements in scientific research, and they discuss here the latest aspects in the diagnosis, disease management, and treatment of hereditary tumor diseases and syndromes.A must-have ready reference for medical and biology students, MDs, PhDs, physicians, and researchers. 606 $aTumors$xGenetic aspects 606 $aCancer$xGenetic aspects 615 0$aTumors$xGenetic aspects. 615 0$aCancer$xGenetic aspects. 676 $a616.994042 701 $aAllgayer$b H$g(Heike),$f1969-$0924340 701 $aRehder$b Helga$0924341 701 $aFulda$b Simone$0924342 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910143141903321 996 $aHereditary tumors$92074317 997 $aUNINA