LEADER 03251oam 2200745zu 450 001 9910142650203321 005 20210721060833.0 010 $a0-470-84654-2 010 $a9786610555444 010 $a1-280-55544-0 035 $a(CKB)111056485557304 035 $a(SSID)ssj0000147114 035 $a(PQKBManifestationID)11151097 035 $a(PQKBTitleCode)TC0000147114 035 $a(PQKBWorkID)10016003 035 $a(PQKB)10127026 035 $a(MiAaPQ)EBC4957428 035 $a(Au-PeEL)EBL4957428 035 $a(CaONFJC)MIL55544 035 $a(OCoLC)1024267238 035 $a(EXLCZ)99111056485557304 100 $a20160829d2002 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEndocrine facets of ageing 210 31$a[Place of publication not identified]$cJohn Wiley & Sons$d2002 215 $a1 online resource (298 pages) 225 1 $aNovartis Foundation Symposia ;$vv.Vol. 242 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-471-48636-1 311 $a0-470-85188-0 330 $aSocial and medical developments have recently led to a dramatic increase in life expectancy. This has inspired the study of organismic changes associated with healthy ageing, in particular the erosion of homeostatic capabilities in multiple endocrine systems. This book reviews advances in the understanding of endocrine facets of ageing. It considers the relative magnitudes and time courses of different endocrine adaptations in the ageing human and experimental animal, addressing the influence of external factors on the rates of progression of endocrine sequelae in ageing, the mechanisms that underlie the disarray of endocrine axes in ageing, and the implications of therapeutic reconstitution of hormones in ageing. This book: considers the mechanisms of ageing and hormonal changes that occur with age; discusses healthy ageing and the relationships between hormonal changes and pathophysiological conditions such as atherosclerosis and age-related bone loss; and draws together contributions from basic and clinical research, to identify and stimulate promising new research directions. 410 0$aNovartis Foundation Symposia 606 $aAnatomy 606 $aGrowth and Development 606 $aPhysiological Processes 606 $aPhysiological Phenomena 606 $aPhenomena and Processes 606 $aAging 606 $aEndocrine System 606 $aHuman Anatomy & Physiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 606 $aPhysiology$2HILCC 608 $aElectronic books. 615 2$aAnatomy 615 2$aGrowth and Development 615 2$aPhysiological Processes 615 2$aPhysiological Phenomena 615 2$aPhenomena and Processes 615 2$aAging 615 2$aEndocrine System 615 7$aHuman Anatomy & Physiology 615 7$aHealth & Biological Sciences 615 7$aPhysiology 676 $a612.67 702 $aChadwick$b Derek 702 $aGoode$b Jamie 801 0$bPQKB 906 $aBOOK 912 $a9910142650203321 996 $aEndocrine facets of ageing$91934527 997 $aUNINA