LEADER 04398nam 2200709 a 450 001 9910141508203321 005 20200520144314.0 010 $a1-118-52699-6 010 $a1-299-14083-1 010 $a1-118-52618-X 035 $a(CKB)2670000000327486 035 $a(EBL)1119533 035 $a(OCoLC)812081275 035 $a(SSID)ssj0000819574 035 $a(PQKBManifestationID)11517660 035 $a(PQKBTitleCode)TC0000819574 035 $a(PQKBWorkID)10845539 035 $a(PQKB)10615557 035 $a(SSID)ssj0000831990 035 $a(PQKBManifestationID)11476911 035 $a(PQKBTitleCode)TC0000831990 035 $a(PQKBWorkID)10880810 035 $a(PQKB)10887846 035 $a(MiAaPQ)EBC1119533 035 $a(Au-PeEL)EBL1119533 035 $a(CaPaEBR)ebr10653587 035 $a(CaONFJC)MIL445333 035 $a(PPN)174726325 035 $a(EXLCZ)992670000000327486 100 $a20121002d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClick chemistry in glycoscience$b[electronic resource] $enew developments and strategies /$fedited by Zbigniew J. Witczak, Roman Bielski 210 $aHoboken, N.J. $cWiley$dc2013 215 $a1 online resource (404 p.) 225 0 $aWiley series in biotechnology and bioengineering Risk management applications in pharmaceutical and biopharmaceutical products manufacturing 300 $aDescription based upon print version of record. 311 $a1-118-27533-0 320 $aIncludes bibliographical references and index. 327 $aParadigm and advantage of carbohydrate click chemistry strategy for future decoupling thio-click chemistry of carbohydrates / Roman Bielski, Zbigniew J. Witczak -- Thio-click chemistry overviews and perspectives / Zbigniew J. Witczak -- Free-radical photoinduced thiol-Ene and thiol-Yne coupling as click processes for glycoconjugation : carbohydrate click chemistry for novel synthetic targets / Alessandro Dondoni, Alberto Marra -- The development and application of clickable lipid analogs for elucidating lipid function / Michael Best -- Clicking sugars onto sugars : oligosaccharide analogue and glycoclusters on carbohydrate scaffolds / Maria Laura Uhrig, Jose Kovensky -- Click multivalent glycomaterials : glycoclusters, glycodendrimers, glycopolymers, hybrid glycomatrials, and glycosurfaces / Carmen Ortiz Mellet ... [et al.] -- Toward imaging glycotools by click coupling / Yves Chapleur, Christine Vala, Sandrine Lamande-Langle -- Bioorthogonal reactions for labeling glycoconjugates / Frederic Friscourt, Geert-Jan Boons -- Sweet sucrose macrocycles via click chemistry route : carbohydrate click chemistry in biomedical sciences / Mykhaylo A. Potopnyk, Slawomir Jarosz -- Neoglycoprotein synthesis using copper-catalyzed azide-alkyne click reaction and native chemical ligation / Joanna M. Wojnar ... [et al.] -- Click-modified cyclodextrin for biomedical application / Dang Wang -- Traizolyl glycoconjugates in medicinal chemistry / Rama Pati Tripathi ... [et al.] -- Click chemistry applied to carbohydrate-based drug discovery / Vanness Leiria Campo, Ivone Carvalho. 330 $a Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps Research Institute in 2001, click chemistry mimics nature, giving researchers the tools needed to generate new substances quickly and reliably by joining small units together. With contributions from more than thirty pioneering researchers in the field, this text explores the many promising applications of click chemistry in glycoscience. Readers will learn both the basic concepts of carbohydrate click chemistry as well as its many biomedical appl 606 $aCarbohydrates 606 $aPolysaccharides 606 $aSystems biology 606 $aCombinatorial chemistry 615 0$aCarbohydrates. 615 0$aPolysaccharides. 615 0$aSystems biology. 615 0$aCombinatorial chemistry. 676 $a572/.567 701 $aWitczak$b Zbigniew J.$f1947-$0285729 701 $aBielski$b Roman$f1946-$0872446 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910141508203321 996 $aClick chemistry in glycoscience$91947728 997 $aUNINA