LEADER 03886nam 2200625Ia 450 001 9910141335403321 005 20230801221837.0 010 $a1-280-58641-9 010 $a9786613616241 010 $a1-4443-5562-7 010 $a1-4443-5543-0 035 $a(CKB)2670000000154959 035 $a(EBL)861626 035 $a(OCoLC)777375710 035 $a(SSID)ssj0000612087 035 $a(PQKBManifestationID)11362726 035 $a(PQKBTitleCode)TC0000612087 035 $a(PQKBWorkID)10685963 035 $a(PQKB)11465483 035 $a(MiAaPQ)EBC861626 035 $a(Au-PeEL)EBL861626 035 $a(CaPaEBR)ebr10538630 035 $a(CaONFJC)MIL361624 035 $a(EXLCZ)992670000000154959 100 $a20111102d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aImmunotherapy in transplantation$b[electronic resource] $eprinciples and practice /$fedited by Bruce Kaplan, Gilbert J. Burckart, Fadi G. Lakkis 210 $aWest Sussex $cJohn Wiley$d2012 215 $a1 online resource (485 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-8271-7 320 $aIncludes bibliographical references and index. 327 $aImmunotherapy in Transplantation: Principles and Practice; Contents; List of Contributors; Preface; Part 1 Transplantation Immunobiology; 1 The Immune Response to a Transplanted Organ: An Overview; 2 Antigen Presentation in Transplantation; 3 The T Cell Response to Transplantation Antigens; 4 The B Cell Response to Transplantation Antigens; 5 The Innate Response to a Transplanted Organ; 6 Regulation of the Alloimmune Response; Part 2 Transplantation Clinical Pharmacology; 7 Pharmacokinetics; 8 Therapeutic Drug Monitoring for Immunosuppressive Agents 327 $a9 Pharmacometrics: Concepts and Applications to Drug Development10 Pharmacogenomics and Organ Transplantation; 11 Study Design/Process of Development: Clinical Studies; Part 3 Agents; 12 Corticosteroids; 13 Azathioprine; 14 Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate; 15 Cyclosporine: Molecular Action to Clinical Therapeutics; 16 Tacrolimus; 17 Inhibitors of Mammalian Target of Rapamycin; 18 Inhibitors Targeting JAK3; 19 Cyclophosphamide; 20 Application of Antisense Technology in Medicine; 21 The Role of Ganciclovir in Transplantation 327 $a22 Transplantation Immunotherapy with Antithymocyte Globulin (ATG)23 The Role of Alemtuzumab in Solid Organ Transplantation; 24 Rituximab, an Anti-CD20 Monoclonal Antibody; 25 The Anti-Interleukin 2 Receptor Antibodies; 26 Infliximab/Anti-TNF; 27 CTLA4-Ig; 28 Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade; 29 Intravenous Immunoglobulin (IVIG) a Modulator of Immunity and Inflammation with Applications in Solid Organ Transplantation; Index; Color Plates 330 $aThis comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system. Compiled by a team of world-renowned editors and contributors covering the fields of transplantation, nephrology, pharmacology, and immunology, the book covers all anti-rejection drugs according to a set template and includes the efficacy of each for specific diseases. 606 $aImmunotherapy 606 $aTransplantation immunology 615 0$aImmunotherapy. 615 0$aTransplantation immunology. 676 $a615.37 701 $aKaplan$b Bruce$f1958-$0948468 701 $aBurckart$b Gilbert J$0948469 701 $aLakkis$b Fadi G$0948470 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910141335403321 996 $aImmunotherapy in transplantation$92144026 997 $aUNINA