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100   $a20110408d2011      uy             0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
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200 00$aPharmacogenetics and individualized therapy$b[electronic resource] /$fedited by Anke-Hilse Maitland-van der Zee, Ann K. Daly
210   $aHoboken, N.J. $cJohn Wiley & Sons$dc2011
215   $a1 online resource (506 p.)
300   $aDescription based upon print version of record.
311   $a0-470-43354-X 
320   $aIncludes bibliographical references and index.
327   $aPharmacogenetics : a historical perspective / A.K. Daly -- Pharmacogenetics in drug metabolism : role of phase I enzymes / V. Dolzan -- Pharmacogenetics of phase II drug metabolizing enzymes / I. Cascorbi -- Pharmacogenetics of drug transporters / Henriette E. Meyer zu Schwabedissen, Markus Grube, Heyo K. Kroemer -- Pharmacogenetics of drug targets / M.Arranz and A. Daly -- Cardiovascular pharmacogenetics / Bas J.M. Peters ... [et al.] -- Pharmacogenetics in psychiatry / Evangelia M. Tsapakis ... [et al.] -- Pharmacogenetics in cancer / S. Marsh -- Pharmacogenetics of asthma and COPD / E. Koster ... [et al.] -- Pharmacogenetics of adverse drug reactions / Ann K Daly, Martin Armstrong, and Munir Pirmohamed -- Pharmacogenomics of inflammatory bowel diseaes / Alexander Teml ... [et al.] -- Pharmacogenetics of pain medication / J. Loetsch -- Ethical and social issues in pharmacogenomics testing / S. Vijverberg, T. Pieters, and M. Cornel -- High-throughput genotyping technologies for pharmacogenetics / Beatriz Sobrino and Dr. Angel Carracedo -- Developments in analyses in pharmacogenetic datasets / A. Motsinger -- Applications of pharmacogenetics in pharmaceutical research and development / Daniel K. Burns and Scott S. Sundseth -- Role of pharmacogenetics in registration process / Myong-Jin Kim ... [et al.] -- Pharmacogenetics : possibilities and pitfalls / A.H. Maitland-van der Zee and A.K. Daly.
330   $aThis resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific disease areas, including cardiovascular, psychiatry, cancer, asthma/COPD, adverse drug reactions, transplantation, inflammatory bowel disease, and pain medication. Clinical practice and ethical issues make up the third section, with the fourth devoted to technologies like genotyping, genomics, and proteomics. In the fifth part,
606   $aPharmacogenetics
615  0$aPharmacogenetics.
676   $a615/.19
701   $aMaitland-van der Zee$b Anke-Hilse$0920868
701   $aDaly$b Ann K$0920869
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801  1$bMiAaPQ
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996   $aPharmacogenetics and individualized therapy$92065450
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