LEADER 02964nam 2200613 a 450 001 9910141288603321 005 20230801222242.0 010 $a1-280-59094-7 010 $a9786613620774 010 $a9781119942986 010 $a1-118-30540-X 010 $a1-119-94298-5 010 $a1-119-94297-7 035 $a(CKB)2670000000170075 035 $a(EBL)881533 035 $a(OCoLC)770696945 035 $a(SSID)ssj0000635051 035 $a(PQKBManifestationID)11451926 035 $a(PQKBTitleCode)TC0000635051 035 $a(PQKBWorkID)10643250 035 $a(PQKB)11648434 035 $a(MiAaPQ)EBC881533 035 $a(DLC) 2012000005 035 $a(Au-PeEL)EBL881533 035 $a(CaPaEBR)ebr10630592 035 $a(CaONFJC)MIL362077 035 $a(EXLCZ)992670000000170075 100 $a20111223d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEvidence synthesis for decision making in healthcare$b[electronic resource] /$fNicky J. Welton ... [et al.] 210 $aChichester, West Sussex $cJohn Wiley & Sons$d2012 215 $a1 online resource (296 p.) 225 0$aStatistics in practice 300 $aDescription based upon print version of record. 311 $a0-470-06109-X 320 $aIncludes bibliographical references and index. 327 $aIntroduction -- Bayesian methods and winBUGS -- Introduction to decision models -- Meta-analysis using Bayesian methods -- Exploring between study heterogeneity -- Model critique and evidence consistency in random effects meta-analysis -- Evidence synthesis in a decision modelling framework -- Multi-parameter evidence synthesis in epidemiological models -- Mixed treatment comparisons -- Markov models -- Generalised evidence synthesis -- Expected value of information for research prioritisation and study design. 330 $aIn the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixe 410 0$aStatistics in practice. 606 $aEvidence-based medicine$xStatistical methods 615 0$aEvidence-based medicine$xStatistical methods. 676 $a362.1068/4 701 $aWelton$b Nicky J$0947329 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910141288603321 996 $aEvidence synthesis for decision making in healthcare$92140410 997 $aUNINA