LEADER 03078nam 2200745 a 450 001 9910141174903321 005 20230801221415.0 010 $a1-283-40095-2 010 $a9786613400956 010 $a1-118-14057-5 010 $a1-118-14056-7 010 $a1-118-14054-0 035 $a(CKB)2670000000133910 035 $a(EBL)818464 035 $a(OCoLC)779166476 035 $a(SSID)ssj0000570323 035 $a(PQKBManifestationID)11391071 035 $a(PQKBTitleCode)TC0000570323 035 $a(PQKBWorkID)10592529 035 $a(PQKB)10041775 035 $a(MiAaPQ)EBC818464 035 $a(MiAaPQ)EBC4026263 035 $a(Au-PeEL)EBL818464 035 $a(CaPaEBR)ebr10521393 035 $a(Au-PeEL)EBL4026263 035 $a(CaPaEBR)ebr11104132 035 $a(CaONFJC)MIL340095 035 $a(OCoLC)927494995 035 $a(EXLCZ)992670000000133910 100 $a20110510d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe AH receptor in biology and toxicology$b[electronic resource] /$fedited by Raimo Pohjanvirta 205 $a1st ed. 210 $aHoboken, N.J. $cWiley$dc2012 215 $a1 online resource (558 p.) 300 $aDescription based upon print version of record. 311 $a0-470-60182-5 320 $aIncludes bibliographical references and index. 327 $apt. 1. Historical background -- pt. 2. AHR as a ligand-activated transcription factor -- pt. 3. AHR as a mediator of xenobiotic toxicities : dioxins as a key example -- pt. 4. AHR as a physiological regulator. 330 $aThis book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases. 606 $aPolycyclic aromatic hydrocarbons$xToxicology 606 $aPolycyclic aromatic hydrocarbons$xMetabolism 606 $aDioxins$xToxicology 606 $aDioxins$xMetabolism 606 $aNuclear receptors (Biochemistry) 606 $aTranscription factors 615 0$aPolycyclic aromatic hydrocarbons$xToxicology. 615 0$aPolycyclic aromatic hydrocarbons$xMetabolism. 615 0$aDioxins$xToxicology. 615 0$aDioxins$xMetabolism. 615 0$aNuclear receptors (Biochemistry) 615 0$aTranscription factors. 676 $a572.8/845 701 $aPohjanvirta$b Raimo$0953426 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910141174903321 996 $aThe AH receptor in biology and toxicology$92155587 997 $aUNINA