LEADER 03928nam 2200661Ia 450 001 9910141169703321 005 20200520144314.0 010 $a1-283-40094-4 010 $a9786613400949 010 $a1-118-14049-4 010 $a1-118-14050-8 010 $a1-118-14047-8 035 $a(CKB)2670000000137426 035 $a(EBL)693203 035 $a(OCoLC)775064527 035 $a(SSID)ssj0000576188 035 $a(PQKBManifestationID)11399448 035 $a(PQKBTitleCode)TC0000576188 035 $a(PQKBWorkID)10553393 035 $a(PQKB)11684154 035 $a(MiAaPQ)EBC693203 035 $a(Au-PeEL)EBL693203 035 $a(CaPaEBR)ebr10523230 035 $a(CaONFJC)MIL340094 035 $a(PPN)243342209 035 $a(EXLCZ)992670000000137426 100 $a20110510d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTopical and transdermal drug delivery$b[electronic resource] $eprinciples and practice /$fedited by Heather A. E. Benson, Adam C. Watkinson 210 $aHoboken, N.J. $cWiley$dc2011 215 $a1 online resource (464 p.) 300 $aDescription based upon print version of record. 311 $a0-470-45029-0 320 $aIncludes bibliographical references and index. 327 $aTransdermal and Topical Drug Delivery Principles and Practice; Contents; Preface; About the Editors; Contributors; Part One: Current Science, Skin Permeation, and Enhancement Approaches; Chapter 1: Skin Structure, Function, and Permeation; Chapter 2: Passive Skin Permeation Enhancement; Chapter 3: Electrical and Physical Methods of Skin Penetration Enhancement; Chapter 4: Clinical Applications of Transdermal Iontophoresis; Chapter 5: In Vitro Skin Permeation Methodology; Chapter 6: Skin Permeation Assessment: Tape Stripping; Chapter 7: Skin Permeation Assessment: Microdialysis 327 $aChapter 8: Skin Permeation: Spectroscopic MethodsChapter 9: Skin Permeation Assessment in Man: In Vitro-In Vivo Correlation; Chapter 10: Risk Assessment; Part Two: Topical and Transdermal Product Development; Chapter 11: An Overview of Product Development from Concept to Approval; Chapter 12: Regulatory Aspects of Drug Development for Dermal Products; Chapter 13: Toxicological and Pre-clinical Considerations for Novel Excipients and New Chemical Entities; Chapter 14: Topical Product Formulation Development; Chapter 15: Transdermal Product Formulation Development 327 $aChapter 16: Sensitivity and Irritation TestingChapter 17: New Product Development for Transdermal Drug Delivery: Understanding the Market Opportunity; Chapter 18: Transdermal and Topical Drug Delivery Today; Chapter 19: Current and Future Trends: Skin Diseases and Treatment; Index 330 $aPractical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emp 606 $aDrug delivery systems 606 $aSkin absorption 606 $aTransdermal medication 615 0$aDrug delivery systems. 615 0$aSkin absorption. 615 0$aTransdermal medication. 676 $a615/.19 701 $aBenson$b Heather A. E$0944848 701 $aWatkinson$b Adam C$0944849 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910141169703321 996 $aTopical and transdermal drug delivery$92133143 997 $aUNINA