LEADER 03583nam 2200601Ia 450 001 9910140905303321 005 20170815145225.0 010 $a1-118-09775-0 010 $a1-282-88343-7 010 $a9786612883439 010 $a0-470-60866-8 010 $a0-470-60865-X 035 $a(CKB)2670000000054699 035 $a(EBL)698781 035 $a(OCoLC)694580088 035 $a(SSID)ssj0000414004 035 $a(PQKBManifestationID)11265423 035 $a(PQKBTitleCode)TC0000414004 035 $a(PQKBWorkID)10384951 035 $a(PQKB)10406112 035 $a(MiAaPQ)EBC698781 035 $a(EXLCZ)992670000000054699 100 $a20091203d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aChiral separation methods for pharmaceutical and biotechnological products$b[electronic resource] /$fSatinder Ahuja 210 $aHoboken, N.J. $cWiley$dc2011 215 $a1 online resource (508 p.) 300 $aDescription based upon print version of record. 311 $a0-470-40691-7 320 $aIncludes bibliographical references and index. 327 $aCHIRAL SEPARATION METHODS FOR PHARMACEUTICAL AND BIOTECHNOLOGICAL PRODUCTS; CONTENTS; Contributors; Preface; 1 Overview of Chiral Separations; 2 Regulatory and Development Considerations of Chiral Compounds; 3 Basic Considerations in HPLC Method Development of Chiral Compounds; 4 Separation of Chiral Compounds on Polysaccharide Columns; 5 Chiral Separations by Various Techniques; 6 Chiral Discrimination Study for Polysaccharide-Based Chiral Stationary Phases; 7 Comparison of Chiral Chromatography Columns for Pharmaceutical Method Development 327 $a8 Chiral Screening Methods for Pharmaceutical Analysis and Purification in an Industrial Laboratory9 Separation of Enantiomers by Gas Chromatography on Chiral Stationary Phases; 10 Separations of Chiral Compounds by SFC; 11 Chiral Separations by Capillary Electrophoresis; 12 High-Throughput Screening and Method Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC, and CE; 13 Use of Enantioselective Synthesis and Preparative Chiral Chromatography to Access a Challenging Enantiopure Pharmaceutical Candidate from a Mixture of Four Stereoisomers 327 $a14 A Look into the Future: Chiral Analysis Using Chemical Sensor Technology15 Chirality of Biomolecules and Biotechnology Products; Index 330 $aDiscusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into 606 $aChiral drugs$xSeparation 606 $aEnantiomers$xSeparation 608 $aElectronic books. 615 0$aChiral drugs$xSeparation. 615 0$aEnantiomers$xSeparation. 676 $a615.19 676 $a615/.19 700 $aAhuja$b Satinder$f1933-$091542 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910140905303321 996 $aChiral separation methods for pharmaceutical and biotechnological products$92250862 997 $aUNINA