LEADER 04013nam 2200637Ia 450 001 9910140858903321 005 20170809171455.0 010 $a1-282-88971-0 010 $a9786612889714 010 $a3-527-63326-X 010 $a3-527-63324-3 010 $a3-527-63325-1 035 $a(CKB)2670000000055453 035 $a(EBL)602643 035 $a(OCoLC)699474437 035 $a(SSID)ssj0000477765 035 $a(PQKBManifestationID)11326961 035 $a(PQKBTitleCode)TC0000477765 035 $a(PQKBWorkID)10512932 035 $a(PQKB)10076884 035 $a(MiAaPQ)EBC602643 035 $a(EXLCZ)992670000000055453 100 $a20100129d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMonolithic silicas in separation science$b[electronic resource] $econcepts, syntheses, characterization, modeling and applications /$fedited by Klaus K. Unger, Nobuo Tanaka, and Egidijus Machtejevas 210 $aWeinheim $cWiley-VCH$dc2011 215 $a1 online resource (364 p.) 300 $aDescription based upon print version of record. 311 $a3-527-32575-1 320 $aIncludes bibliographical references and index. 327 $aMonolithic Silicas in Separation Science; Contents; Preface; List of Contributors; 1: The Basic Idea and the Drivers; 1.2: Monoliths as Heterogeneous Catalysts; 1.3: Monoliths in Chromatographic Separations; 1.4: Conclusion and Perspectives; References; Part One: Preparation; 2: Synthesis Concepts and Preparation of Silica Monoliths; 3: Preparation and Properties of Various Types of Monolithic Silica Stationary Phases for Reversed-Phase, Hydrophilic Interaction, and Ion-Exchange Chromatography Based on Polymer-Coated Materials; Part Two: Characterization and Modeling 327 $a4: Characterization of the Pore Structure of Monolithic Silicas5: Microscopic Characterizations; 6: Modeling Chromatographic Band Broadening in Monolithic Columns; 7.1: Introduction; 7.2: Basic Columns Properties; 7.3: Comparison of the Through-Pore Structures and Related Properties; 7.4: Thermodynamic Properties; 7.5: Kinetic Properties and Column Efficiency; 7.6: Conclusions; Part Three: Applications; 8: Quantitative Structure-Retention Relationships in Studies of Monolithic Materials; 9: Performance of Silica Monoliths for Basic Compounds. Silanol Activity; 10: Quality Control of Drugs 327 $a11: Monolithic Stationary Phases for Fast Ion Chromatography12: Monolithic Chiral Stationary Phases for Liquid-Phase Enantioseparation Techniques; 13: High-Speed and High-Efficiency Separations by Utilizing Monolithic Silica Capillary Columns; 14: Silica Monolithic Columns and Mass Spectrometry; 15: Silica Monoliths for Small-Scale Purification of Drug-Discovery Compounds; 16: Monolithic Silica Columns in Multidimensional LC-MS for Proteomics and Peptidomics; 17.1: Introduction; 17.2: Extraction Process; 17.3: Extraction Platforms; 17.4: Applications; 17.5: Conclusion and Outlook; References 327 $aIndex 330 $aEdited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must-have information hitherto only scattered among journals.Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists. 606 $aSeparation (Technology) 606 $aSilica 608 $aElectronic books. 615 0$aSeparation (Technology) 615 0$aSilica. 676 $a546.68 676 $a546.683 701 $aMachtejevas$b Egidijus$0981836 701 $aTanaka$b Nobuo$096771 701 $aUnger$b K. K$g(Klaus K.),$f1936-$0273428 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910140858903321 996 $aMonolithic silicas in separation science$92240776 997 $aUNINA