LEADER 05636nam 2200721 450 001 9910140644103321 005 20230803072441.0 010 $a1-119-07000-7 010 $a1-119-07077-5 035 $a(CKB)2670000000616819 035 $a(EBL)1896043 035 $a(SSID)ssj0001482359 035 $a(PQKBManifestationID)11904142 035 $a(PQKBTitleCode)TC0001482359 035 $a(PQKBWorkID)11432066 035 $a(PQKB)10987042 035 $a(MiAaPQ)EBC1896043 035 $a(Au-PeEL)EBL1896043 035 $a(CaPaEBR)ebr11055106 035 $a(CaONFJC)MIL785575 035 $a(OCoLC)900278010 035 $a(PPN)191886475 035 $a(EXLCZ)992670000000616819 100 $a20150527h20152015 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMass spectrometry for the analysis of pesticide residues and their metabolites /$fedited by Despina Tsipi, Helen Botitsi, Anastasios Economou 210 1$aHoboken, New Jersey :$cJohn Wiley & Sons, Inc.,$d2015. 210 4$dİ2015 215 $a1 online resource (291 p.) 225 1 $aWiley Series on Mass Spectrometry 225 1 $aTHEi Wiley ebooks 300 $aDescription based upon print version of record. 311 $a1-119-06998-X 311 $a1-118-50017-2 320 $aIncludes bibliographical references and index. 327 $aTitle Page; Copyright Page; Contents; List of Contributors; Foreword; Preface; Chapter 1 Pesticide Chemistry and Risk Assessment; 1.1 INTRODUCTION; 1.2 PESTICIDE CHEMISTRY; 1.2.1 Historical Perspective; 1.2.2 Identity and Physicochemical Properties of Pesticides; 1.2.3 Pesticide Classification; 1.2.4 Modes of Action (MoA); 1.3 PESTICIDE METABOLITES AND TRANSFORMATION PRODUCTS; 1.3.1 Biotransformation; 1.3.2 Environmental Fate; 1.4 RISK ASSESSMENT; 1.4.1 Safety Factors; 1.4.2 Ecological Risk Assessment for Pesticides; 1.5 DIETARY EXPOSURE TO PESTICIDES 327 $a1.5.1 Acute Exposure or Short-Term Intake 1.5.2 Chronic Exposure or Long-Term Intake; 1.5.3 Cumulative Exposure to Multiple Substances; 1.6 PESTICIDE RESIDUES IN FOOD; 1.6.1 Maximum Residue Limits; 1.6.2 Residue Definition; 1.6.3 Reporting of Results; 1.6.4 Residue Analysis; REFERENCES; Chapter 2 Legislation, Monitoring, and Analytical Quality Control for Pesticide Residues; 2.1 INTRODUCTION; 2.2 FOOD SAFETY; 2.2.1 CAC of Food and Agriculture Organization/World Health Organization; 2.2.2 EU Legislation; 2.2.3 US Food Regulations; 2.3 WATER QUALITY; 2.3.1 WHO; 2.3.2 EU Water Framework Directive 327 $a2.3.3 US EPA Legislation 2.4 METHOD VALIDATION AND QUALITY CONTROL PROCEDURES FOR PESTICIDE RESIDUES ANALYSIS; 2.4.1 CAC Guidelines; 2.4.2 EU Guidelines: SANCO Document; 2.4.3 FDA and EPA Guidelines; REFERENCES; Chapter 3 Advanced Sample Preparation Techniques for MS Analysis; 3.1 INTRODUCTION; 3.2 CONVENTIONAL EXTRACTION AND CLEANUP PROCEDURES; 3.2.1 LLE; 3.2.2 SPE; 3.2.3 MSPD; 3.2.4 QuEChERS; 3.3 MICROEXTRACTION TECHNIQUES; 3.3.1 Sorbent-Based Microextraction Techniques; 3.3.2 Liquid-Based Microextraction Techniques; 3.4 ALTERNATIVE EXTRACTION AND CLEANUP PROCEDURES 327 $a3.4.1 Alternative Energy Sources to Enhance the Extraction 3.4.2 Coupled-Column Liquid Chromatography (LC/PC, LC/LC Techniques); 3.4.3 Direct Analysis in Real Time; 3.5 CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; Chapter 4 Recent Developments in Gas Chromatography-Mass Spectrometry; 4.1 INTRODUCTION; 4.2 ADVANCES IN GC SEPARATIONS; 4.2.1 Multidimensional and Comprehensive Two-Dimensional Gas Chromatography; 4.2.2 Fast GC; 4.2.3 LPGC; 4.3 MASS SPECTROMETRIC IONIZATION TECHNIQUES; 4.3.1 Electron Impact Ionization (EI); 4.3.2 CI (Positive/Negative Modes); 4.3.3 Atmospheric Pressure GC-MS 327 $a4.4 MASS ANALYZERS INTERFACED TO GC 4.4.1 Quadrupole Mass Analyzer; 4.4.2 Ion Trap Mass Analyzer; 4.4.3 QqQ; 4.4.4 TOF; 4.5 MASS SPECTRAL LIBRARIES AND SOFTWARE APPROACHES IN GC-MS ANALYSIS; 4.6. MATRIX EFFECTS IN GC-MS ANALYSIS; 4.7 CONCLUSIONS AND PERSPECTIVES; REFERENCES; Chapter 5 Recent Developments in Liquid Chromatography-Mass Spectrometry: Advances in Liquid Chromatographic Separations and Ionization Techniques/Interfaces; 5.1 INTRODUCTION; 5.2 ADVANCES IN LIQUID CHROMATOGRAPHIC SEPARATIONS; 5.2.1 Ultraperformance Liquid Chromatography 327 $a5.2.2 Hydrophilic Interaction Liquid Chromatography 330 $aProvides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites. Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in combination with MS for the analysis of pesticides Describes various established and new 410 0$aWiley-Interscience series on mass spectrometry. 410 0$aTHEi Wiley ebooks. 606 $aPesticides$xAnalysis 606 $aMass spectrometry 615 0$aPesticides$xAnalysis. 615 0$aMass spectrometry. 676 $a632/.95 702 $aTsipi$b Despina 702 $aBotitsi$b Helen 702 $aEconomou$b Anastassios 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910140644103321 996 $aMass spectrometry for the analysis of pesticide residues and their metabolites$92130255 997 $aUNINA