LEADER 03016nam 2200649Ia 450 001 9910140567603321 005 20170815150529.0 010 $a1-118-03181-4 010 $a1-282-65355-5 010 $a9786612653551 010 $a0-470-57270-1 010 $a0-470-57269-8 035 $a(CKB)2670000000029538 035 $a(EBL)547051 035 $a(OCoLC)646788370 035 $a(SSID)ssj0000426330 035 $a(PQKBManifestationID)11281222 035 $a(PQKBTitleCode)TC0000426330 035 $a(PQKBWorkID)10373783 035 $a(PQKB)10392501 035 $a(MiAaPQ)EBC547051 035 $a(PPN)163568383 035 $a(EXLCZ)992670000000029538 100 $a20090710d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aProtein misfolding diseases$b[electronic resource] $ecurrent and emerging principles and therapies /$fedited by Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson 210 $aHoboken, N.J. $cWiley$dc2010 215 $a1 online resource (1102 p.) 225 1 $aWiley series on protein and peptide science 300 $aDescription based upon print version of record. 311 $a0-471-79928-9 320 $aIncludes bibliographical references and index. 327 $aPROTEIN MISFOLDING DISEASES; CONTENTS; CONTRIBUTORS; FOREWORD; PREFACE; ACKNOWLEDGMENTS; INTRODUCTION TO THE WILEY SERIES ON PROTEIN AND PEPTIDE SCIENCE; PART I PRINCIPLES OF PROTEIN MISFOLDING; PART II PROTEIN MISFOLDING DISEASE: GAIN-OF-FUNCTION AND LOSS-OF-FUNCTION DISEASES; PART III ROLE OF ACCESSORY MOLECULES AND RISK FACTORS; PART IV MEDICAL ASPECTS OF DISEASE: DIAGNOSIS AND CURRENT THERAPIES; PART V APPROACHES FOR NEW AND EMERGING THERAPIES; INDEX 330 $aAn increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific researchers, and doctors working with protein misfolding diseases bridge the gap between basic science and pharmaceutical applications to protein misfolding disease. 410 0$aWiley series in protein and peptide science. 606 $aProteins$xMetabolism$xDisorders 606 $aProtein folding 606 $aAmyloidosis 615 0$aProteins$xMetabolism$xDisorders. 615 0$aProtein folding. 615 0$aAmyloidosis. 676 $a616.3/995 676 $a616.3995 701 $aRamirez-Alvarado$b Marina$0932368 701 $aKelly$b Jeffery W$091720 701 $aDobson$b C. M$g(Christopher M.)$0932369 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910140567603321 996 $aProtein misfolding diseases$92097978 997 $aUNINA