LEADER 05440nam 2200697 450 001 9910140280003321 005 20200520144314.0 010 $a3-527-66753-9 010 $a3-527-66751-2 010 $a3-527-66754-7 035 $a(CKB)2670000000534444 035 $a(EBL)1643668 035 $a(SSID)ssj0001189736 035 $a(PQKBManifestationID)11777548 035 $a(PQKBTitleCode)TC0001189736 035 $a(PQKBWorkID)11177189 035 $a(PQKB)10430725 035 $a(MiAaPQ)EBC1643668 035 $a(MiAaPQ)EBC4044479 035 $a(Au-PeEL)EBL1643668 035 $a(CaPaEBR)ebr10845584 035 $a(CaONFJC)MIL580596 035 $a(OCoLC)871781411 035 $a(PPN)21988174X 035 $a(EXLCZ)992670000000534444 100 $a20140320h20142014 uy 0 101 0 $ager 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aLithium compounds in organic synthesis $efrom fundamentals to applications /$fedited by Renzo Luisi and Vito Capriati 210 1$aWeinheim, Germany :$cWiley-VCH Verlag,$d2014. 210 4$dİ2014 215 $a1 online resource (571 p.) 300 $aDescription based upon print version of record. 311 $a3-527-33343-6 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aLithium Compounds in Organic Synthesis; Contents; List of Contributors; Foreword; Preface; Part I New Structural Aspects of Lithium Compounds; Chapter 1 Structure-Reactivity Relationship in Organolithium Compounds; 1.1 Structural Principles in Organolithium Compounds; 1.2 Donor-Base-Free Structures; 1.2.1 Tetramers; 1.2.2 Hexamers; 1.2.3 Comparison of [Me3SiCH2Li]6 and [n-BuLi]6; 1.3 Disaggregation with Lewis Bases; 1.3.1 Tetramers of Alkyllithium Compounds; 1.3.2 Asymmetric Aggregates of [Me3SiCH2Li] (4); 1.3.3 An Octameric Aggregate of [Me3SiCH2Li]6 327 $a1.4 Donor-Base-Induced Dimers and Monomers1.4.1 Alkyllithium and Trimethylsilylmethyllithium Compounds; 1.4.2 PMDETA Aggregated Monomers; 1.5 Heterobimetallic Organolithium Compounds; 1.6 Conclusion and Outlook; References; Further Reading; Chapter 2 Computational Perspectives on Organolithiums; 2.1 Introduction; 2.2 The Nature of Bonds to Lithium; 2.3 Aggregation of Lithium Organic Compounds; 2.4 Solvation Effects; 2.5 Lithium Alkoxides and Lithium Amides; 2.6 Computational Studies on Various Organolithium Applications; 2.7 Conclusion and Outlook; References; Further Reading 327 $aChapter 3 Spectroscopic Advances in Organolithium Reactivity: The Contribution of Rapid-Injection NMR (RINMR)3.1 Introduction; 3.2 The Curtin-Hammett Principle; 3.3 Organolithium NMR; 3.4 Features of RINMR; 3.4.1 Brief History; 3.4.2 Apparatus Descriptions and Rapidity of Acquisition; 3.4.3 Temperature Range and Control; 3.4.4 Volume Accuracy of Injection; 3.5 Use of RINMR to Study Organometallic Reactions; 3.5.1 n-Butyllithium Aggregate Reactivity (1985); 3.5.2 Magnesium Chelates in Carbonyl Additions (1987/1990); 3.5.3 Lithium Enolate Aldol (1992) 327 $a3.5.4 Alkyllithium Polymerization (1995/1999)3.5.5 Tin Transmetallation (2007); 3.5.6 Cuprates (2002-Present); 3.5.7 n-BuLi Aggregate Reactivity Revisited (2007); 3.5.8 Tris(trimethylsilyl)methyllithium (2008/2009); 3.5.9 Enolization and Lithium Aldol (2011); 3.6 Conclusion and Outlook; References; Further Reading; Chapter 4 Spectroscopic Advances in Structural Lithium Chemistry: Diffusion-Ordered Spectroscopy and Solid-State NMR; 4.1 General Introduction; 4.2 Application of Solution NMR to the Structural Characterization of Organolithium Compounds; 4.2.1 Diffusion NMR Measurement Methods 327 $a4.2.1.1 Pulsed Field Gradient Spin Echo (PFGSE)4.2.1.2 From the First to the Second Dimension: DOSY NMR Experiment; 4.2.2 DOSY Application to the Structural Analysis of Organolithium Compounds; 4.2.2.1 Structure of the Mixed Methyllithium/Lithium Chloride Aggregate; 4.2.2.2 Structure of a Lithium Phosphido-Borane; 4.2.2.3 Structure of Lithium Zincate; 4.2.3 Conclusion; 4.3 Solid-State NMR; 4.3.1 Basic Principles; 4.3.1.1 Homo and Heteronuclear Dipole-Dipole Couplings (D: Dipole-Dipole); 4.3.1.2 Chemical Shift Anisotropy (CSA); 4.3.1.3 Quadrupolar Interactions for Nuclei with I< 1/2 (Q) 327 $a4.3.1.4 Magic Angle Spinning (MAS) 330 $a This unique book covers fundamentals of organolithium compounds and gives a comprehensive overview of the latest synthetic advances and developments in the field. Part I covers computational and spectroscopic aspects as well as structure-reactivity relationships of organolithiums, whereas Part II deals with new lithium-based synthetic methodologies as well as novel synthetic applications of functionalized lithium compounds. A useful resource for newcomers and active researchers involved in organic synthesis, whether working in academia or industry! 606 $aCyclic compounds 606 $aLithium compounds 606 $aOrganic compounds$xSynthesis 615 0$aCyclic compounds. 615 0$aLithium compounds. 615 0$aOrganic compounds$xSynthesis. 676 $a547.05381 702 $aLuisi$b Renzo 702 $aCapriati$b Vito 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910140280003321 996 $aLithium compounds in organic synthesis$91996687 997 $aUNINA