LEADER 05362nam 2200661Ia 450 001 9910139963403321 005 20170815105935.0 010 $a1-282-34947-3 010 $a9786612349478 010 $a0-470-74469-3 010 $a0-470-74468-5 035 $a(CKB)1000000000822242 035 $a(EBL)470355 035 $a(OCoLC)352790036 035 $a(SSID)ssj0000290069 035 $a(PQKBManifestationID)11911091 035 $a(PQKBTitleCode)TC0000290069 035 $a(PQKBWorkID)10404898 035 $a(PQKB)11181513 035 $a(MiAaPQ)EBC470355 035 $a(PPN)243300158 035 $a(EXLCZ)991000000000822242 100 $a20081231d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiomedical applications of electroactive polymer actuators$b[electronic resource] /$fFederico Carpi, Elisabeth Smela 210 $aChichester, West Sussex ;$aHoboken $cJohn Wiley & Sons$d2009 215 $a1 online resource (506 p.) 300 $aDescription based upon print version of record. 311 $a0-470-77305-7 320 $aIncludes bibliographical references and index. 327 $aBiomedical Applications of Electroactive Polymer Actuators; Contents; Preface; List of Contributors; Introduction; SECTION I POLYMER GELS; 1 Polymer Gel Actuators: Fundamentals; 1.1 Introduction and Historical Overview; 1.2 Properties of Gels; 1.2.1 Biological Gels; 1.2.2 Mechanical Properties of Simple, Single-Phase Gels; 1.2.3 Elastic Moduli; 1.2.4 Strength; 1.2.5 Multi-Phase Gels; 1.2.6 Double Network Gels; 1.2.7 Transport Properties; 1.2.8 Drying; 1.3 Chemical and Physical Formation of Gels; 1.4 Actuation Methods; 1.4.1 Thermally Driven Gel Actuators 327 $a1.4.2 Chemically Driven Gel Actuators1.4.3 Gels Driven by Oscillating Reactions; 1.4.4 Light Actuated Gels; 1.4.5 Electrically Driven Gel Actuators; 1.4.6 Electro- and Magneto-Rheological Composites; 1.4.7 LC Elastomers; 1.5 Performance of Gels as Actuators; 1.6 Applications of Electroactive Gels; 1.6.1 Gel Valves and Pumps; 1.6.2 Light Modulators; 1.6.3 Gel Drug Delivery; 1.6.4 Gel Sensors; 1.7 Conclusions; References; 2 Bio-Responsive Hydrogels for Biomedical Applications; 2.1 Introduction; 2.2 Chemical Hydrogels; 2.3 Physical Hydrogels; 2.4 Defining Bio-Responsive Hydrogels 327 $a2.5 Bio-Responsive Chemical Hydrogels2.5.1 Actuation Based on Changing the Cross-Linking Density; 2.5.2 Actuation Based on Changes in Electrostatic Interactions; 2.5.3 Actuation Based on Conformational Changes; 2.6 Bio-Responsive Physical Hydrogels; 2.6.1 Enzyme-Responsive Physical Hydrogels; 2.7 Electroactive Chemical Hydrogels; 2.8 Conclusion; References; 3 Stimuli-Responsive and 'Active' Polymers in Drug Delivery; 3.1 Introduction; 3.2 Drug Delivery: Examples, Challenges and Opportunities for Polymers; 3.2.1 Oral Drug Delivery Systems; 3.2.2 Parenteral Drug Delivery 327 $a3.2.3 Topical and Transdermal Drug Delivery3.2.4 Delivery Challenges for Biomolecular Drugs and Cell Therapeutics; 3.2.5 Peptides and Proteins; 3.2.6 Nucleic Acids; 3.2.7 Cell Delivery; 3.3 Emerging State-of-the-Art Mechanisms in Polymer Controlled Release Systems; 3.3.1 Technologies for Controlled Drug Release; 3.3.2 Polymer-Drug Conjugates; 3.3.3 Polymer-Protein Conjugates; 3.3.4 Polymer-Nucleic Acid Conjugates; 3.3.5 Polymer-Nucleic Acid Complexes; 3.4 Responsive or 'Smart' Polymers in Drug Delivery; 3.4.1 Soluble Smart Polymers; 3.4.2 Responsive Polymer-Drug Conjugates 327 $a3.4.3 Responsive Polymer-Protein Conjugates3.4.4 Responsive Polymers for DNA Delivery; 3.5 Recent Highlights of Actuated Polymers for Drug Delivery Applications; 3.6 Conclusions and Future Outlook; References; 4 Thermally Driven Hydrogel Actuator for Controllable Flow Rate Pump in Long-Term Drug Delivery; 4.1 Introduction; 4.2 Materials and Methods; 4.3 Hydrogel Actuator; 4.3.1 Thermo-Mechanical Gel Dynamics; 4.3.2 Experimental Results; 4.4 Pump Functioning; 4.5 Conclusion; References; SECTION II IONIC POLYMER-METAL COMPOSITES (IPMC); 5 IPMC Actuators: Fundamentals; 5.1 Introduction 327 $a5.2 Fabrication 330 $aGiving fundamental information on one of the most promising families of smart materials, electroactive polymers (EAP) this exciting new titles focuses on the several biomedical applications made possible by these types of materials and their related actuation technologies. Each chapter provides a description of the specific EAP material and device configuration used, material processing, device assembling and testing, along with a description of the biomedical application. Edited by well-respected academics in the field of electroactive polymers with contributions from renowned international 606 $aPolymers in medicine 606 $aConducting polymers 606 $aActuators 615 0$aPolymers in medicine. 615 0$aConducting polymers. 615 0$aActuators. 676 $a610.28/4 676 $a610.284 700 $aCarpi$b Federico$f1975-$0973839 701 $aSmela$b Elisabeth$0973840 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139963403321 996 $aBiomedical applications of electroactive polymer actuators$92216379 997 $aUNINA