LEADER 05663nam 2200721Ia 450 001 9910139950603321 005 20200520144314.0 010 $a1-282-27929-7 010 $a9786612279294 010 $a0-470-43179-2 010 $a0-470-43178-4 035 $a(CKB)1000000000790511 035 $a(EBL)455899 035 $a(OCoLC)609844622 035 $a(SSID)ssj0000354321 035 $a(PQKBManifestationID)11256490 035 $a(PQKBTitleCode)TC0000354321 035 $a(PQKBWorkID)10302859 035 $a(PQKB)10272060 035 $a(MiAaPQ)EBC455899 035 $a(Au-PeEL)EBL455899 035 $a(CaPaEBR)ebr10332981 035 $a(CaONFJC)MIL227929 035 $a(OCoLC)441875020 035 $a(PPN)145512150 035 $a(EXLCZ)991000000000790511 100 $a20080728d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHistological analysis of endocrine disruptive effects in small laboratory fish$b[electronic resource] /$fDaniel R. Dietrich, Heiko O. Keiger 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2009 215 $a1 online resource (388 p.) 300 $aDescription based upon print version of record. 311 $a0-471-76358-6 320 $aIncludes bibliographical references and index. 327 $aHISTOLOGICAL ANALYSIS OF ENDOCRINE DISRUPTIVE EFFECTS IN SMALL LABORATORY FISH; CONTENTS; Preface; Acknowledgments; Contributing Authors; 1 Introduction; References; 2 Fish Species of Interest; 2.1 Fathead Minnow (Pimephales promelas); 2.2 Medaka (Oryzias latipes); 2.3 Zebrafish (Danio rerio); 2.4 Other Fish Species; References; 3 Sexual Determination, Differentiation, and Gonadal Development; 3.1 Primordial Germ Cells in the Primordial (Primary) Gonad; 3.1.1 Differentiation and Number of PGCs; 3.1.2 Molecular Markers of PGCs; 3.2 Reproductive Strategies 327 $a3.3 Differentiation of the Primordial Gonad into Ovary or Testis3.4 Gonadal Duct Formation; 3.5 Endocrinology: Influence on Gonadogenesis; 3.6 Critical Period of Sexual Differentiation in Developing Fish; 3.7 Bi-Potentiality of Germ Cells in Adult Fish; References; 4 Female Gonad Anatomy and Morphology; 4.1 Gonadogenesis: Ovary; 4.1.1 Location and Gross Organization; 4.1.2 Anatomy of the Ovary; 4.2 Hypothalamic-Pituitary-Ovarian Axis; 4.3 Cellular Structure of the Ovary; 4.3.1 Germ Cells (Oogenesis); 4.3.2 Female Somatic Supportive Tissue; 4.3.2.1 Theca Cells; 4.3.2.2 Granulosa Cells 327 $aReferences5 Male Gonad Anatomy and Morphology; 5.1 Gonadogenesis: Testes; 5.1.1 Location and Gross Organization; 5.1.2 Anatomy of the Testes; 5.1.3 Germinal Epithelium; 5.1.4 Male Germ Cells (Spermatogenesis); 5.1.5 Male Somatic Supportive Tissue; 5.1.5.1 Sertoli Cells; 5.1.5.2 Leydig Cells; 5.1.5.3 Lobule Boundary Cells; 5.1.5.4 Sex Steroid Control of Spermatogenesis; References; 6 Endocrine-Disrupting Compounds; 6.1 Individual Effects; 6.1.1 Inhibition of Gametogenesis; 6.1.2 Necrosis and Apoptosis (Gamete and Stromal Cells); 6.1.3 Atretic Follicles 327 $a6.1.4 Sertoli Cell Hypertrophy and Hyperplasia6.1.5 Leydig Cell Hypertrophy and Hyperplasia; 6.1.6 Fibrosis; 6.1.7 Gonadal Duct Formation; 6.2 Effects Associated with Exposure to Specific Compounds or Compound Classes; Table 6.1 Overt Testicular Changes in Male Fish; Table 6.2 Testis-Ova in Male Fish; Table 6.3 Testicular Fibrosis in Male Fish; Table 6.4 Germ Cell Effects in Male Fish; Table 6.5 Somatic Cell Effects in Male Fish; Table 6.6 Testicular Inflammation and Macrophage Infiltration in Male Fish; Table 6.7 Overt Ovarian Changes in Female Fish 327 $a Table 6.8 Ovo-Testis in Female Fish Table 6.9 Ovarian Fibrosis in Female Fish; Table 6.10 Germ Cell Effects in Female Fish; Table 6.11 Germ Cell Atresia in Female Fish; Table 6.12 Ovarian Inflammation and Macrophage Infiltration in Female Fish; 6.2.1 Effects in Male Fish Associated with Exposure to Specific Compounds or Compound Classes; 6.2.1.1 Testis Architecture, Integrity, and Gross Appearance; 6.2.1.2 Testis-Ova; 6.2.1.3 Fibrosis; 6.2.1.4 Germ Cell Effects; 6.2.1.5 Somatic Cell Effects; 6.2.1.6 Testicular Cell Inflammation and Macrophage Infiltration 327 $a6.2.2 Effects in Female Fish Associated with Exposure to Specific Compounds or Compound Classes 330 $aTimely title assembling the combined knowledge of some of the leading authorities in the field of small fish reproduction - an important topic for risk assessment and registration of chemical, agricultural, and pharmaceutical compoundsProvides guidance on the microscopic structure of living tissue and evaluation of the reproductive glands of small laboratory fishIncludes state-of-the-art science along with sufficient anatomical and physiological background for understanding and interpreting test resultsHelps standardize the interpretation of results from aquatic bioassays a 606 $aEndocrine disrupting chemicals 606 $aHistology, Pathological 606 $aFishes$xEndocrinology 606 $aFishes$xEffect of chemicals on 615 0$aEndocrine disrupting chemicals. 615 0$aHistology, Pathological. 615 0$aFishes$xEndocrinology. 615 0$aFishes$xEffect of chemicals on. 676 $a616.4/06 700 $aDietrich$b Daniel R$0943614 701 $aKrieger$b Heiko O.$f1972-$0943615 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139950603321 996 $aHistological analysis of endocrine disruptive effects in small laboratory fish$92129940 997 $aUNINA